The outcomes and quality of life of young patients undergoing adjuvant radiotherapy versus non-radiotherapy following surgery treating early FIGO stage cervical squamous cell cancer in southwestern China.

Scientific Reports
LingYun YangHongJing Wang

Abstract

The incidence of cervical cancer in young women is rising, and squamous cell carcinoma makes up a great percentage of the histological types. The presence of aggressive pathologic risk factors following patients' primary surgery may warrant the use of adjuvant radiotherapy. It is important to weigh up the risks and benefits of using adjuvant radiotherapy for each young patient so as to maximize their prognosis while minimizing the treatment-related morbidity. A retrospective study was performed. It consisted of 97 patients under 35 years old who were diagnosed with cervical squamous cell carcinoma and underwent treatment at West China Second University Hospital between December 2009 and January 2014. Five-year follow-up, prognostic risks, long-term radiation toxicity, female sexual function, and quality of life were investigated. Adjuvant radiotherapy did improve the prognosis of young patients with lymph node metastases. However, there were few significant differences in progress-free survival and overall survival for the young patients without lymph node metastases following adjuvant radiotherapy. Besides, young patients who took radiotherapy exhibited greater intestinal dysfunction, more severe lower extremities edema, great...Continue Reading

References

Jan 1, 1984·Acta Radiologica. Oncology·B Lantz, N Einhorn
Mar 30, 1995·International Journal of Radiation Oncology, Biology, Physics·J D CoxT F Pajak
Dec 1, 1993·British Journal of Urology·H VirtanenT Hirvonen
Apr 14, 2000·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·W A PetersD S Alberts
Sep 1, 2004·International Journal of Radiation Oncology, Biology, Physics·Kiyoshi OharaHiroyuki Yoshikawa
Aug 28, 2007·BMC Cancer·Vincent Vinh-HungAnne-Thérèse Vlastos
Aug 31, 2007·Gynecologic Oncology·Francesco RaspagliesiRosanna Fontanelli
Oct 30, 2007·Gynecologic Oncology·Thomas J Herzog, Jason D Wright
Jul 29, 2008·Current Opinion in Supportive and Palliative Care·Martin Hauer-JensenJames W Denham
Jan 17, 2009·CA: a Cancer Journal for Clinicians·Brian D LawendaPeter A S Johnstone
Mar 9, 2012·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Jin Hwi KimSoo Young Hur
May 18, 2012·The Cochrane Database of Systematic Reviews·Linda RogersHeather O Dickinson
Jan 27, 2015·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Nicoletta BigliaAchtari Chahin
Feb 6, 2015·CA: a Cancer Journal for Clinicians·Lindsey A TorreAhmedin Jemal
Aug 12, 2018·Scientific Reports·Niresh ThapaHongbing Cai
Jan 9, 2019·CA: a Cancer Journal for Clinicians·Rebecca L SiegelAhmedin Jemal

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SPSS

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