PMID: 11911677Mar 26, 2002Paper

The outer membrane fraction of Flavobacterium psychrophilum induces protective immunity in rainbow trout and ayu

Fish & Shellfish Immunology
Habibur RahmanMitsuru Ototake

Abstract

Flavobacterium psychrophilum is the causative agent of coldwater disease, which is responsible for serious losses in fish aquaculture in several parts of the world. No commercial vaccines are currently available for the prevention of coldwater disease. The present study sought to assess the efficacy of a F. psychrophilum vaccine based on the antigenic outer membrane fraction (OMF). This fraction induced significantly higher protection against coldwater disease in both rainbow trout (Oncorhynchus mykiss) and ayu (Plecoglossus altivelis) compared to inactivated whole cell F. psychrophilum bacterin. Coincident with higher protection, sera of fish immunised with the OMF vaccine had higher agglutination titres than those of fish immunised with inactivated whole cell F. psychrophilum.

Citations

Jan 27, 2006·Journal of Fish Diseases·M E Nielsen, M D Esteve-Gassent
Jul 25, 2014·Microbial Biotechnology·Esther GómezJosé A Guijarro
Jul 30, 2004·Journal of Applied Microbiology·B MassiasM Le Hénaff
Jan 5, 2017·Bioscience, Biotechnology, and Biochemistry·Hitoshi NakayamaKenichi Amano
Feb 21, 2014·Diseases of Aquatic Organisms·Goshi KatoChihaya Nakayasu
Jan 11, 2011·Applied and Environmental Microbiology·Shohreh HesamiJanet I Macinnes
Sep 18, 2014·Journal of Aquatic Animal Health·Eric J Wagner, Randall W Oplinger
Dec 5, 2003·Journal of Fish Diseases·A NematollahiF Haesebrouck
Jul 28, 2004·Fish & Shellfish Immunology·M Dolores Esteve-Gassent, Carmen Amaro

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