PMID: 8599265Jan 1, 1995Paper

The oxygen status of fetal blood

Acta Anaesthesiologica Scandinavica. Supplementum
O Siggaard-Andersen, R Huch

Abstract

To estimate the acid-base and oxygen status of fetal blood and compare with maternal placental venous blood. DATA SOURCES AND CALCULATIONS: We selected pH and blood gas data from the literature pertaining to umbilical vein and artery blood obtained by cordocentesis and estimated values for the 30th and 40th gestational week. Average values for maternal venous blood leaving the placenta were estimated on the assumption of equal maternal arterio-venous and umbilical veno-arterial total oxygen concentration differences. pH and pCO2 of maternal blood leaving the placenta and umbilical vein blood are almost identical at week 30. A small pCO2 and pH difference may exist at week 40. The pO2 of the maternal placental venous blood and umbilical vein blood are almost identical at week 30, but at week 40 a pO2 difference indicates an umbilical arterio-venous shunting of as much as 30%. The fetal mixed venous pO2 falls from 2.6 kPa to 2.2 kPa from the 30th to the 40th gestational week. More accurate measurements are needed to confirm our results. Future measurements should be performed with a combined pH-blood gas analyser and haemoximeter to allow determination of the complete oxygen status of the blood.

References

Jan 1, 1990·Scandinavian Journal of Clinical and Laboratory Investigation. Supplementum·O Siggaard-Andersen, M Siggaard-Andersen
Oct 1, 1989·American Journal of Obstetrics and Gynecology·K H NicolaidesP W Soothill
May 1, 1971·Scandinavian Journal of Clinical and Laboratory Investigation·O Siggaard-Andersen
Jul 1, 1995·Critical Care Medicine·O Siggaard-AndersenV H Larsen
Jan 1, 1995·Acta Anaesthesiologica Scandinavica. Supplementum·M Siggaard-Andersen, O Siggaard-Andersen

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Citations

Jul 11, 2009·International Anesthesiology Clinics·Keira P Mason
Jan 1, 1995·Acta Anaesthesiologica Scandinavica. Supplementum·M Siggaard-Andersen, O Siggaard-Andersen
Aug 30, 2008·Biotechnology and Bioengineering·Daryl E PowersClark K Colton
May 27, 2015·Journal of Evaluation in Clinical Practice·Lukáš HrubanLenka Lhotská
Jan 15, 2014·BMC Pregnancy and Childbirth·Václav ChudáčekLenka Lhotská
Jan 24, 2018·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Ana E Rodríguez-SotoFelix W Wehrli
Oct 6, 2006·Current Opinion in Anaesthesiology·Kim S Khaw, Warwick D Ngan Kee
Sep 22, 2018·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Andrew MelbourneSebastien Ourselin
Sep 26, 2009·Current Opinion in Organ Transplantation·Jeffrey R MillmanClark K Colton
Feb 8, 2005·European Journal of Nutrition·Heidrun Kiwull-SchönePeter Kiwull
Jul 16, 2019·Prenatal Diagnosis·Rosalind AughwaneAndrew Melbourne
Mar 29, 2013·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Dan Rurak, Natalee W Bessette
May 7, 2020·The Journal of Physiology·Brahmdeep S SainiMike Seed
Aug 7, 2010·Journal of Applied Physiology·Steven S LaurieAndrew T Lovering
Dec 20, 2018·Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia·Barbara VonkovaSarka Pospisilova

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