The p38 and p34 polypeptides of growth cone particle membranes are the alpha- and beta-subunits of G proteins

Brain Research. Developmental Brain Research
B T EdmondsL Ellis

Abstract

Growth cone particle (GCP) membranes prepared from fetal day 17 rat brain are comprised of 5 major polypeptides as analyzed by SDS-PAGE: tubulin (p52), actin (p42), pp46/GAP-43 and two unidentified species, p38 and p34. Antibodies specific for the alpha- and beta-subunits of G proteins recognize p38 and p34, respectively, on immunoblots following one- and two-dimensional electrophoretic separation. That G protein subunits comprise major species of GCP membrane-associated polypeptides suggests a role for G proteins in transmembrane signaling in nerve growth cones.

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Jan 1, 1991·Molecular Neurobiology·K H PfenningerS Quiroga
Jun 29, 2007·Neuro-degenerative Diseases·Valentina VeneziaClaudio Russo
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Oct 6, 2020·Frontiers in Cell and Developmental Biology·Daayun ChungGabriela Caraveo
Apr 1, 1995·Journal of Neurobiology·P F CopenhaverM A Rasmussen

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