Jan 19, 2010

The parental dentocraniofacial phenotype-an orofacial clefting microform

The Cleft Palate-craniofacial Journal : Official Publication of the American Cleft Palate-Craniofacial Association
P A MosseyG T McIntyre


Using the systematic review method, (1) to identify the investigations of the parental dentocraniofacial phenotype in orofacial clefting, (2) synthesize the data to derive a model of the phenotypic features that will assist in the identification of cleft morphogenes, and (3) make recommendations for the future global strategy for researching the parental craniofacial phenotype in orofacial clefting. The Cochrane, Medline (via PubMed and OVID platforms [1966 to December 2006]), Embase, CINAHL, and ASKSAM Orthodontic Reference Database (1950-1997) databases were searched using a combination of the following keywords: microform, parent, craniofacial, dental, and cleft. All published articles were reviewed. There were no exclusions of non-English reports. Of the 36 studies identified using this strategy, 26 met the inclusion criteria. DATA ABSTRACTION/SYNTHESIS: The statistically significant data were abstracted using a pro forma, and the methodological quality of the selected studies was evaluated using a checklist. There was considerable heterogeneity among the studies, and therefore it was not possible to synthesize the data. We were, however, able to collate the data. (1) The craniofacial phenotype possessed by parents of child...Continue Reading

  • References46
  • Citations6


  • References46
  • Citations6


Mentioned in this Paper

Dental Models
Bone Structure of Face
Cleft Palate, Isolated
Genetic Inheritance
Cleft Lip With or Without Cleft Palate

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