The pathogenesis and epidemiology of catheter-related infection with pulmonary artery Swan-Ganz catheters: a prospective study utilizing molecular subtyping

The American Journal of Medicine
L A MermelD G Maki

Abstract

To delineate the pathogenesis and epidemiology of catheter-related infection with Swan-Ganz pulmonary artery (PA) catheters, a prospective clinical study of hospitalized adult medical and surgical patients was done. Role of catheter material was assessed by randomizing insertions to heparin-bonded PA catheters made of polyvinylchloride or polyurethane. Sources of infection and pathogenesis were studied by culturing skin, the introducer, the PA catheter tip, all hubs, infusate from each lumen, and the extravascular portion of the PA catheter beneath the external protective plastic sleeve. Concordance between isolates from sources and infected catheters was determined by speciation, antibiogram, and for coagulase-negative staphylococci, plasmid profile analysis. Risk factors for infection were determined by stepwise logistic regression. Overall, 65 (22%) of 297 Swan-Ganz catheters showed local infection of the introducer (58 catheters) or the intravascular portion of the PA catheter (20 catheters); only two catheters (0.7%) caused bacteremia. Eighty percent of infected Swan-Ganz catheters (the introducer or PA catheter) showed concordance with organisms cultured from skin of the insertion site, 17% with a contaminated hub and 18%...Continue Reading

References

Jun 9, 1977·The New England Journal of Medicine·D G MakiH W Sarafin
Feb 1, 1989·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·L A Mermel, D G Maki
Sep 1, 1987·Chest·L PasseriniE G King
Feb 1, 1988·Critical Care Medicine·J H LevyV Tobia
Jan 1, 1988·Intensive Care Medicine·P CollignonP Woods
May 1, 1987·Critical Care Medicine·S O HeardT J Gallagher
Jan 1, 1987·Critical Care Medicine·J A Hudson-CivettaT A Hoffman
Feb 1, 1985·Annals of Surgery·M L MyersW J Sibbald
Jun 1, 1985·American Journal of Surgery·W SamsoondarC Oxley
Feb 21, 1986·JAMA : the Journal of the American Medical Association·R L LuskinS A Kabins
Aug 27, 1970·The New England Journal of Medicine·H J SwanD Chonette
May 1, 1980·The Journal of Infectious Diseases·J T Parisi, D W Hecht
Jan 1, 1984·Intensive Care Medicine·P BaeleY Kestens-Servaye
Jun 1, 1984·The Journal of Infectious Diseases·G L ArcherJ L Johnston
Mar 1, 1981·Annals of Surgery·F T PadbergB R Bistrian
Dec 1, 1981·American Journal of Surgery·A H GraeveW R Schiller
Nov 1, 1982·Critical Care Medicine·S SinghV K Puri
Dec 1, 1980·The British Journal of Surgery·L SmallmanJ Alexander-Williams
Mar 13, 1981·JAMA : the Journal of the American Medical Association·L MichelN S Brewer

❮ Previous
Next ❯

Citations

Jan 1, 1996·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·J VallésA Artigas
Mar 5, 2008·Intensive Care Medicine·Philippe Eggimann, Giorgio Zanetti
Sep 17, 2004·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·L LaurenziE Arcuri
Apr 20, 2004·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Manuel MoralesCésar O Freytes
Apr 4, 2008·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·L LorenteM L Mora
Apr 17, 2009·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·L LorenteM L Mora
Jun 10, 2010·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·R PeredoJ Vallés
Nov 30, 2000·Current Infectious Disease Reports·D P Calfee, B M Farr
Dec 31, 1998·The American Journal of Medicine·S Saint, M A Matthay
Jul 1, 1995·The Journal of Hospital Infection·L A SampathS M Modak
Feb 4, 1998·Critical Care Clinics·G A Bergen, J F Toney
Mar 1, 1996·Nutrition·K A Adal, B M Farr
Feb 13, 1999·Zentralblatt Für Bakteriologie : International Journal of Medical Microbiology·A BachH G Sonntag
Feb 13, 2003·Journal of Vascular and Interventional Radiology : JVIR·Donald L Miller, Naomi P O'Grady
Oct 26, 2000·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·A HumarJ M Conly
Sep 11, 2001·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·D K WarrenV J Fraser
Oct 12, 2001·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·B M Farr
Apr 10, 2002·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Christopher J Crnich, Dennis G Maki
Dec 4, 2002·American Journal of Infection Control·Naomi P O'gradyUNKNOWN Healthcare Infection Control Practices Advisory Committee
Aug 19, 2008·Biomedical Materials·P Fleckman, J E Olerud
Dec 3, 1998·Acta Anaesthesiologica Scandinavica·T WeberR N Sladen
Nov 13, 2008·Seminars in Dialysis·Gerald A Beathard, Aris Urbanes
Jan 28, 1998·American Journal of Respiratory and Critical Care Medicine·Y CohenM Cupa
Jun 5, 2002·American Journal of Respiratory and Critical Care Medicine·Sanjay SaintMichael A Matthay
Feb 3, 2007·BMC Anesthesiology·Nathalie L van der Mee-Marquet, UNKNOWN Bloodstream infection Study Group of the Relais Régional d'Hygiène Hospitalière du Centre
Sep 13, 2011·Annals of Intensive Care·Jean-François TimsitCarole Schwebel
Nov 11, 2005·Critical Care : the Official Journal of the Critical Care Forum·Leonardo LorenteMaría L Mora
Dec 14, 2006·Critical Care : the Official Journal of the Critical Care Forum·Mehrnaz Hadian, Michael R Pinsky
Feb 8, 2013·Journal of Clinical Medicine Research·Ann O'ConnorDeborah A McNamara
Jan 25, 2011·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Peter J PronovostJohn A Jernigan
Jul 16, 2014·International Journal of Critical Illness and Injury Science·Rupam GahlotShampa Anupurba
Apr 5, 2011·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Naomi P O'GradyUNKNOWN Healthcare Infection Control Practices Advisory Committee (HICPAC)
Apr 2, 2011·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Sonali AdvaniAaron M Milstone
Apr 7, 2011·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Naomi P O'GradyUNKNOWN Healthcare Infection Control Practices Advisory Committee (HICPAC) (Appendix 1)
Dec 3, 2014·The Surgical Clinics of North America·Mohamed F Osman, Reza Askari
Mar 1, 1996·Intensive Care Medicine·S E TebbsT S Elliott
Jun 1, 1996·Intensive Care Medicine·A Bach
Jun 6, 2009·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Leonard A MermelDavid K Warren

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