PMID: 6104342DOI: 10.1017/s003329170003960xFeb 1, 1980Paper
The pathophysiology of extrapyramidal side-effects of neuroleptic drugs
Psychological Medicine
C D Marsden, P Jenner
Abstract
The mechanisms responsible for the production of major extrapyramidal side-effects (parkinsonism, akathisia, acute dystonic reactions, chronic tardive dyskinesias) are reviewed in the light of the complex effects of these drugs on cerebral dopamine systems.
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