The pattern of infiltration at the proximal border of hilar bile duct carcinoma: a histologic analysis of 62 resected cases

Annals of Surgery
E SakamotoK Uesaka

Abstract

To clarify the importance of different patterns of infiltration at the proximal border of hilar bile duct carcinomas. There are few detailed pathologic studies on the proximal resection margins in patients with hilar bile duct carcinoma. Serial sections of 62 specimens of resected hilar bile duct carcinoma were examined histologically to determine the involved layers and routes of invasion at the proximal border. The degree of cancer extension was determined, and the relation between the length of the tumor-free resection margin and postoperative anastomotic recurrences was analyzed. Mucosal extension was predominant in papillary and nodular tumors, but submucosal extension was predominant in diffusely infiltrating and nodular-infiltrating tumors. Submucosal extension usually consisted of direct or lymphatic invasion. The mean length of submucosal extension was 6.0 mm. Superficial spread of cancer, defined as mucosal extension of more than 20 mm from the main lesion, was seen in 8 specimens. No patient had an anastomotic recurrence when the tumor-free resection margin was greater than 5 mm. The pattern of infiltration at the proximal border of resected hilar bile duct carcinomas is closely related to the gross tumor type. The l...Continue Reading

References

Jan 1, 1992·Annals of Surgery·H BismuthT Diamond
Apr 1, 1992·Annals of Surgery·M R BhuiyaS Shionoya
Feb 1, 1988·Annals of Surgery·S BengmarkK G Tranberg
Jan 1, 1988·Surgical Endoscopy·Y NimuraA Yasui
Feb 1, 1983·The Journal of Pathology·K Weinbren, S S Mutum

❮ Previous
Next ❯

Citations

Mar 9, 2006·Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen·M BahraP Neuhaus
Mar 29, 2006·Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen·H LangC E Broelsch
May 7, 2008·European Radiology·Yong Eun ChungJin-Young Choi
Oct 3, 2006·Journal of Hepato-biliary-pancreatic Surgery·Takeshi SasakiEiji Shimozawa
Jul 22, 2006·Journal of Hepato-biliary-pancreatic Surgery·Yoshitsugu NakanishiTomoo Itoh
Oct 3, 2007·Journal of Hepato-biliary-pancreatic Surgery·Michiaki UnnoTadashi Ishibashi
Feb 16, 2008·Journal of Hepato-biliary-pancreatic Surgery·Shuichi MiyakawaUNKNOWN Japan Society of Clinical Oncology
Feb 16, 2008·Journal of Hepato-biliary-pancreatic Surgery·Kazuhiro TsukadaUNKNOWN Japan Society of Clinical Oncology
Oct 7, 2008·Journal of Hepato-biliary-pancreatic Surgery·Marcus BahraPeter Neuhaus
Feb 14, 2009·Journal of Hepato-biliary-pancreatic Surgery·Nobuhisa AkamatsuDaijo Hashimoto
Mar 5, 2009·Journal of Hepato-biliary-pancreatic Surgery·Tsuyoshi IgamiMasato Nagino
Mar 12, 2008·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Kwang Yeol PaikSang Bum Kim
Nov 11, 2009·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Yoshihiro SakamotoTomoo Kosuge
Jan 25, 2012·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Chang-Sup LimSun-Whe Kim
Feb 2, 2013·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Mee Joo KangSun-Whe Kim
Jan 18, 2011·Clinical & Translational Oncology : Official Publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico·Ketao JinLisong Teng
Jun 26, 2009·Journal de chirurgie·K SlimP Valleur
Oct 5, 2001·Journal of the American College of Surgeons·M W MulhollandC J Yeo
Mar 22, 2003·Journal of the American College of Surgeons·Atsutake OkamotoNobuaki Funata
Apr 22, 2008·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Yoshitsugu NakanishiSatoshi Kondo
Jan 25, 2012·Nature Reviews. Gastroenterology & Hepatology·Andrea ParodiMassimo Conio
Feb 18, 2003·Pathology International·Joji HaratakeHiroshi Makino
Oct 28, 1999·The New England Journal of Medicine·P C de GroenD M Nagorney
Oct 7, 2006·Current Opinion in Gastroenterology·J A Ehrenfried, J N Vauthey
Oct 13, 2006·Current Opinion in Gastroenterology·J N Cormier, J N Vauthey
Feb 13, 2009·Annals of Surgery·Tsuyoshi IgamiYoshie Shimoyama
Jul 30, 2009·Annals of Surgery·Fumito ItoSharon M Weber
Dec 15, 2012·Surgical Laparoscopy, Endoscopy & Percutaneous Techniques·Harutoshi SugiyamaOsamu Yokosuka
Jan 16, 2010·Journal of Gastroenterology and Hepatology·Nobuhisa AkamatsuDaijo Hashimoto

❮ Previous
Next ❯

Related Concepts

Related Feeds

Carcinoma, Ductal

Ductal carcinoma is a malignant neoplasm involving the ductal systems of any of a number of organs, such as the mammary glands, pancreas, prostate or lacrimal gland. Discover the latest research on ductal carcinoma here.