The pattern of lipids and lipoproteins during the menopausal transition in Chinese women

Climacteric : the Journal of the International Menopause Society
Y CuiA O Mueck

Abstract

Objective To investigate changes in levels of lipids and lipoproteins in Chinese women during perimenopause and postmenopause as primary study endpoints, for the first time including lipoprotein(a). Methods The retrospective study was performed in 1015 women without hormone therapy aged 34-76 years from 20 provinces of China who visited the Beijing Obstetrics & Gynecology hospital. Menopausal status was defined by the criteria of the 2011 Stages of Reproductive Aging Workshop. Results Levels of total cholesterol, triglycerides and low density lipoprotein (LDL) cholesterol increased and that of high density lipoprotein (HDL) cholesterol decreased in the postmenopausal compared to the perimenopausal group. In the women with body mass index (BMI) ≥ 25 kg/m(2), total cholesterol and LDL cholesterol increased, HDL cholesterol decreased and changes in triglyceride levels were not significant. In the women with BMI < 25 kg/m(2), the increase in triglyceride levels during the transition was significant. Changes in lipoprotein(a), apolipoprotein A1 and apolipoprotein B were not significant. Comparing the groups with BMI ≥ 25 kg/m(2) vs. BMI < 25 kg/m(2), only the differences for apolipoprotein A1 and for triglycerides were significant. ...Continue Reading

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Citations

Oct 14, 2017·Annals of Clinical Biochemistry·John W Honour
May 10, 2018·Climacteric : the Journal of the International Menopause Society·X SunR Chen
Jun 6, 2019·Journal of the American Heart Association·Yiqing WangPenny Gordon-Larsen
Aug 5, 2017·Climacteric : the Journal of the International Menopause Society·Y SunA O Mueck
Mar 19, 2020·Menopause : the Journal of the North American Menopause Society·Veronica InarajaEsteban Jodar

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