The pattern of symptom change during prolonged exposure therapy and present-centered therapy for PTSD in active duty military personnel

Psychological Medicine
Lily A BrownSTRONG STAR Consortium

Abstract

Few studies have investigated the patterns of posttraumatic stress disorder (PTSD) symptom change in prolonged exposure (PE) therapy. In this study, we aimed to understand the patterns of PTSD symptom change in both PE and present-centered therapy (PCT). Participants were active duty military personnel (N = 326, 89.3% male, 61.2% white, 32.5 years old) randomized to spaced-PE (S-PE; 10 sessions over 8 weeks), PCT (10 sessions over 8 weeks), or massed-PE (M-PE; 10 sessions over 2 weeks). Using latent profile analysis, we determined the optimal number of PTSD symptom change classes over time and analyzed whether baseline and follow-up variables were associated with class membership. Five classes, namely rapid responder (7-17%), steep linear responder (14-22%), gradual responder (30-34%), non-responder (27-33%), and symptom exacerbation (7-13%) classes, characterized each treatment. No baseline clinical characteristics predicted class membership for S-PE and M-PE; in PCT, more negative baseline trauma cognitions predicted membership in the non-responder v. gradual responder class. Class membership was robustly associated with PTSD, trauma cognitions, and depression up to 6 months after treatment for both S-PE and M-PE but not for ...Continue Reading

References

Aug 17, 2002·Journal of Consulting and Clinical Psychology·Pallavi NishithMichael G Griffin
Mar 1, 2007·JAMA : the Journal of the American Medical Association·Paula P SchnurrNancy Bernardy
Jan 6, 2009·Learning & Behavior·Gonzalo P UrcelayRalph R Miller
Jul 29, 2009·Journal of Traumatic Stress·Kacie A KellyPatricia A Resick
Feb 23, 2010·Behavior Therapy·Alyssa J OrinsteinRalph R Miller
Mar 23, 2010·Behaviour Research and Therapy·Lisa Stines DoaneLori A Zoellner
Jul 27, 2011·Journal of Consulting and Clinical Psychology·Idan M AderkaEva Gilboa-Schechtman
May 2, 2013·Depression and Anxiety·Janie J JunNorah C Feeny
Dec 26, 2013·JAMA : the Journal of the American Medical Association·Edna B FoaDavid Rosenfield
Sep 1, 2015·Clinical Psychology Review·Amanda G LoerincMichelle G Craske
Jan 6, 2016·Behaviour Research and Therapy·Sadie E LarsenPatricia A Resick
Jun 21, 2016·Depression and Anxiety·Joshua D ClappPeter W Tuerk

❮ Previous
Next ❯

Citations

Jul 12, 2021·Journal of Psychiatric Research·Philip HeldNiranjan S Karnik

❮ Previous
Next ❯

Related Concepts

Related Feeds

Anxiety Disorders

Discover the latest research on anxiety disorders including agoraphobia, panic disorder, obsessive-compulsive disorder, and post-traumatic stress disorder here.