PMID: 9543365Apr 16, 1998Paper

The paucity of minimal change disease in adolescents with primary nephrotic syndrome

Pediatric Nephrology : Journal of the International Pediatric Nephrology Association
N BaqiA Tejani

Abstract

Data are sparse regarding the histological lesions associated with the primary nephrotic syndrome in adolescents. To our knowledge there are only two published articles that have specifically addressed the histopathological lesions that typify idiopathic nephrotic syndrome in the adolescent population. We reviewed our experience from the last 14 years of children between the ages of 12 and 18 years who were referred to our center for the evaluation of the nephrotic syndrome. A total of 29 adolescents met the inclusion criteria for this review. All patients were biopsied prior to the initiation of treatment. The sex ratio consisted of 52% males and 48% females and the racial breakdown was largely African-American, with 83% black adolescents, 7% Hispanic, and 10% Caucasian patients. Minimal change nephrotic syndrome (MCNS), the predominant lesion of children at an early age, was noted in only 20% of patients. The majority of patients (55.2%) had focal segmental glomerulosclerosis (FSGS); 7% had IgM nephropathy and 3.5% had diffuse mesangial hypercellularity. Only 7% of biopsied adolescents had membranoproliferative glomerulonephritis. Our results indicate that the most common lesion in this predominantly African-American patient ...Continue Reading

Citations

Sep 13, 2006·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Rajendra BhimmaKareshma Asharam
Dec 8, 2006·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Ronald HoggV Matti Vehaskari
Oct 15, 2008·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Neveen A SolimanGil Chernin
Aug 29, 2003·Lancet·Allison A Eddy, Jordan M Symons
May 7, 1999·Kidney International·M Bonilla-FelixR Verani
May 10, 2011·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Muhammed MubarakFazal Akhter
Apr 15, 1999·Current Opinion in Pediatrics·R W Chesney
Aug 18, 2005·Kidney International·Jung Sue KimV Matti Vehaskari
Dec 13, 2006·American Journal of Nephrology·Rajendra BhimmaCatherine Connolly
Jun 7, 2007·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Fábio Fernandes BorgesPaulo Cesar Koch Nogueira
Jun 1, 2012·Kidney International Supplements
May 26, 2004·Clinical Science·José G van den Berg, Jan J Weening

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Pediatric Nephrology : Journal of the International Pediatric Nephrology Association
W R GriswoldH Spiegelberg
Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association
A Schmidt, G Mayer
Pediatric Nephrology : Journal of the International Pediatric Nephrology Association
T SrivastavaU S Alon
© 2022 Meta ULC. All rights reserved