The PediaFlow pediatric ventricular assist device

Seminars in Thoracic and Cardiovascular Surgery. Pediatric Cardiac Surgery Annual
Peter WeardenRobert E Shaddy

Abstract

The very limited options available to treat ventricular failure in patients with congenital and acquired heart diseases have motivated the development of a pediatric ventricular assist device (VAD). Our effort involves a consortium consisting of the University of Pittsburgh, Carnegie Mellon University, Children's Hospital of Pittsburgh, World Heart Corporation, and LaunchPoint Technologies, LLC. The overall aim of our program is to develop a highly reliable, biocompatible VAD for chronic support (6 months) of the unique and high-risk population of children between 3 kg and 15 kg (patients from birth to 2 years of age). The innovative pediatric VAD we are developing (PediaFlow) is based on a miniature mixed-flow turbodynamic pump featuring magnetic levitation, with the design goal being to assure minimal blood trauma and risk of thrombosis. This article discusses the limitations of current pediatric cardiac assist treatment options and the work to date by our consortium toward the development of a pediatric VAD.

References

Jul 1, 1995·Artificial Organs·K K YeleswarapuK R Rajagopal
Feb 27, 1999·The Journal of Thoracic and Cardiovascular Surgery·B W DuncanJ M Wilson
Feb 2, 2000·The Annals of Thoracic Surgery·A E IbrahimR A Jonas
Jan 17, 2002·The New England Journal of Medicine·E A RoseUNKNOWN Randomized Evaluation of Mechanical Assistance for the Treatment of Congestive Heart Failure (REMATCH) Study Group
May 23, 2002·The Annals of Thoracic Surgery·Brian W Duncan
Jul 9, 2002·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Daniel LeviHillel Laks
Sep 26, 2002·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Olaf ReinhartzDavid J Farrar
Nov 5, 2003·AACN Clinical Issues·Virginia Fidrocki Mason, Annette Jakubisin Konicki
Dec 6, 2003·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Olaf ReinhartzDavid J Farrar
Feb 11, 2005·The Thoracic and Cardiovascular Surgeon·M DeiwickH H Scheld
Apr 1, 2005·European Heart Journal·Michael P SiegenthalerFriedhelm Beyersdorf
Jun 2, 2005·Artificial Organs·Jingchun WuBradley E Paden
Jun 14, 2005·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Brigitte StillerRoland Hetzer
Jul 2, 2005·Journal of Pediatric Surgery·Jae-O BaeCharles J H Stolar
Sep 28, 2005·Artificial Organs·Ingo KaczmarekSabine Daebritz
Dec 3, 2005·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Mahesh S SharmaRobert L Kormos
Dec 3, 2005·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Jingchun WuHarvey S Borovetz

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Citations

Nov 29, 2007·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Kurt A DasseHarvey S Borovetz
Sep 25, 2008·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·S Adil HusainMark W Turrentine
Nov 30, 2019·Expert Review of Medical Devices·Roland HetzerEva Maria Javier Delmo
Jun 23, 2007·Biomedical Chromatography : BMC·Suresh C V BabuYoung Sook Yoo
May 29, 2018·The Journal of Thoracic and Cardiovascular Surgery·Salim E OliaJames F Antaki
Nov 17, 2020·Artificial Organs·Harutyun SarkisyanAmy Throckmorton

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