The pelvic retroperitoneal approach in the treatment of advanced ovarian carcinoma

Obstetrics and Gynecology
P Benedetti-PaniciS Mancuso

Abstract

To evaluate the feasibility, complications, and clinical role of pelvic cytoreduction using the retroperitoneal approach in the treatment of advanced ovarian cancer. We studied 66 women with previously untreated advanced ovarian cancer who underwent pelvic retroperitoneal surgery. The possibility of achieving extrapelvic cytoreduction (residual disease less than 2 cm), involvement of the Douglas cul-de-sac or vesicouterine fold, or the presence of a frozen pelvis were indications for the retroperitoneal approach. Operative time, blood loss and transfusions, perioperative complications, and postoperative stay were analyzed prospectively. The performance status of each patient was assessed preoperatively and postoperatively. The pelvic retroperitoneal approach was used in 66 of 147 (45%) consecutive patients who underwent primary surgery with intent of cytoreduction. This approach was necessary in 60 of 94 (64%) patients with residual tumor less than 0.5 cm and contributed to achieving such a minimal residual disease in 36 of 38 (95%) stage IIB-IIIB and 58 of 109 (53%) IIIC-IV patients. Severe morbidity, but with no long-term sequelae, occurred in six (9%) patients. Before surgery, only ten (15%) of these patients had a performan...Continue Reading

References

Nov 1, 1992·Gynecologic Oncology·S M EisenkopH J Wang
Aug 1, 1991·Gynecologic Oncology·W BarnesG Delgado
Mar 1, 1989·Baillière's Clinical Obstetrics and Gynaecology·M J Webb
Mar 1, 1989·Baillière's Clinical Obstetrics and Gynaecology·J M Monaghan
Dec 1, 1982·Gynecologic Oncology·J G Blythe, T P Wahl
Dec 1, 1982·American Journal of Clinical Oncology·M M OkenP P Carbone
Jul 1, 1993·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·J.E. BridgesA.J. McCartney

❮ Previous
Next ❯

Citations

Dec 10, 1999·Critical Reviews in Oncology/hematology·P F ConteA Gadducci
Oct 3, 2003·Journal of the American College of Surgeons·Robert E BristowFredrick J Montz
Jan 22, 2002·Current Opinion in Obstetrics & Gynecology·Angiolo Gadducci
Feb 6, 2008·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·A Gadducci, P F Conte
Oct 7, 2008·Gynecologic Oncology·Mitchel S Hoffman, Emmanuel Zervose
Jul 13, 2005·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·M A RousseauG Saillant
Sep 29, 2011·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·V GallottaA Fagotti
Aug 13, 2011·The Cochrane Database of Systematic Reviews·Ahmed ElattarRaj Naik
Oct 30, 2018·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Selçuk ErkilinçMuzaffer Sanci
Jul 4, 2009·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Gilles HouvenaeghelDamien Castaigne
May 28, 2019·Minerva medica·Salvatore Gueli AllettiGiovanni Scambia

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.