The penetration of dapsone, rifampicin, isoniazid and pyrazinamide into peripheral nerves.

British Journal of Pharmacology
B W AllenA G Weddell

Abstract

1 Dapsone, rifampicin, isoniazid and pyrazinamide were shown to penetrate readily into the sciatic nerves of the dog and sheep. 2 These findings suggest that the continued persistence of viable drug-sensitive leprosy bacilli in the peripheral nerves of patients treated for long periods with either dapsone or rifampicin is not due to inadequate intraneural drug penetration.

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Citations

Jul 13, 1979·Acta Neuropathologica·J M JacobsJ B Cavanagh
Aug 1, 1979·British Journal of Urology·J G Gow
Aug 1, 1995·Antimicrobial Agents and Chemotherapy·M Guebre-XabierD Frommel
Oct 14, 1983·Biochemical and Biophysical Research Communications·R Rajagopalan, S Gurnani
Oct 1, 1985·Biochemical Pharmacology·R Rajagopalan, S Gurnani

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