PMID: 590266Nov 15, 1977

The peptidoglycan crosslinking enzyme system in Streptomyces strains R61, K15 and rimosus

European Journal of Biochemistry
M Leyh-BouilleH R Perkins

Abstract

The DD-carboxypeptidase-transpeptidase enzyme system in Streptomyces strain K15 consists of: (1) a membrane-bound transpeptidase capable of performing low DD-carboxypeptidase activity; and (2) a set of DD-carboxypeptidases: (a) membrane-bound, (b) lysozyme-releasable and (c) exocellular, having low transpeptidase activities in aqueous media and at low acceptor concentrations. The DD-carboxypeptidases are related to each other and may belong to the same pathway leading to enzyme excretion. A similar enzyme system occurs in Streptomyces strain R61 except that the membrane-bound DD-carboxypeptidase activity is low when compared with the membrane-bound transpeptidase activity. In Streptomyces rimosus the enzyme system consists almost exclusively of the membrane-bound transpeptidase and the levels of membrane-bound, lysozyme-releasable and exocellular DD-carboxypeptidases are very low.

References

Sep 1, 1977·European Journal of Biochemistry·S T ShepherdP E Reynolds
Nov 15, 1977·European Journal of Biochemistry·M Nguyen-DistècheJ M Ghuysen
Jan 1, 1976·Methods in Enzymology·J M FrèreH R Perkins
Aug 15, 1975·European Journal of Biochemistry·R A Laskey, A D Mills
Nov 15, 1973·Journal of Molecular Biology·U K Laemmli, M Favre
Aug 1, 1974·European Journal of Biochemistry·A MarquetH R Perkins
Jul 1, 1974·European Journal of Biochemistry·W M Bonner, R A Laskey
May 25, 1971·Biochemistry·M Leyh-BouilleM Nieto

Citations

Mar 1, 1979·European Journal of Biochemistry·D Mirelman, Y Nuchamowitz
Jan 1, 1980·Antimicrobial Agents and Chemotherapy·H Ogawara, S Horikawa
Sep 7, 2002·Journal of Molecular Biology·Michael A McDonoughJ A Kelly
Jan 1, 1985·Critical Reviews in Microbiology·J M Frère, B Joris
Nov 15, 1977·European Journal of Biochemistry·M Nguyen-DistècheJ M Ghuysen
Apr 1, 1981·European Journal of Biochemistry·M Leyh-BouilleJ M Ghuysen

Related Concepts

Muramoylpentapeptide Carboxypeptidase
Carboxypeptidase
Plasma Membrane
Lysosomes
Pseudomurein
Streptomyces

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Bacterial cell walls are made of peptidoglycan (also called murein), which is made from polysaccharide chains cross-linked by unusual peptides containing D-amino acids. Here is the latest research on bacterial cell wall structures.

Bacterial Cell Wall Structure

Bacterial cell walls are made of peptidoglycan (also called murein), which is made from polysaccharide chains cross-linked by unusual peptides containing D-amino acids. Here is the latest research on bacterial cell wall structures.