The Persistence of Escherichia coli Infection in German Cockroaches (Blattodea: Blattellidae) Varies Between Host Developmental Stages and is Influenced by the Gut Microbiota

Journal of Medical Entomology
Ritesh RayJose E Pietri

Abstract

The German cockroach, Blatella germanica (L.), is a suspected vector of several enteric bacterial pathogens, including Escherichia coli, among livestock and humans. However, little is known about the factors that influence bacterial transmission by cockroaches. Here, we orally infected B. germanica with various laboratory and field strains of E. coli and examined bacterial titers over time to shed new light on the factors that influence the dynamics of infection. Our results reveal that a laboratory strain of E. coli is largely cleared within 48 h while one field isolate can persist in a majority of cockroaches (80-100%) for longer than 3 d with minimal impact on cockroach longevity. We also find that the ability to clear some strains of E. coli is greater in cockroach nymphs than adults. Notably, no differential expression of the antimicrobial gene lysozyme was observed between nymphs and adults or in infected groups. However, clearance of E. coli was significantly reduced in gnotobiotic cockroaches that were reared in the absence of environmental bacteria, suggesting a protective role for the microbiota against exogenous bacterial pathogens. Together, these results demonstrate that the interactions between cockroaches and ent...Continue Reading

References

May 16, 2000·The Journal of Allergy and Clinical Immunology·P W FinnD R Gold
May 29, 2002·The EMBO Journal·Ennio De GregorioBruno Lemaitre
Jan 18, 2005·Clinical Microbiology Reviews·Thaddeus K GraczykLeena Tamang
Apr 4, 2006·Environmental Health Perspectives·Richard D CohnDarryl C Zeldin
Jun 13, 2008·Nature Protocols·Thomas D Schmittgen, Kenneth J Livak
Jul 21, 2011·Frontiers in Microbiology·Brian M M Ahmer, John S Gunn
Oct 25, 2011·Cell Host & Microbe·Chris M CirimotichGeorge Dimopoulos
Mar 20, 2013·Frontiers in Physiology·Ioannis EleftherianosJulio C Castillo
Aug 10, 2013·Journal of Medical Entomology·Dana Nayduch, Chester Joyner
Apr 8, 2014·Applied and Environmental Microbiology·Ludek Zurek, Anuradha Ghosh
Apr 29, 2014·Pathogens and Global Health·Taha MenasriaHaroun Chenchouni
Jan 15, 2015·Current Opinion in Insect Science·Nathan J DennisonGeorge Dimopoulos
Mar 10, 2015·Briefings in Functional Genomics·Lumi Viljakainen
Mar 13, 2015·FEMS Microbiology Ecology·Ana Elena Pérez-CobasAmparo Latorre
Dec 9, 2015·Proceedings of the National Academy of Sciences of the United States of America·Ayako Wada-KatsumataCoby Schal
Dec 27, 2015·Allergy·D C DoP Gao
May 6, 2017·Immunity, Inflammation and Disease·Danh C DoPeisong Gao
Nov 28, 2017·Scientific Reports·Ana Carolina M JunqueiraStephan C Schuster
Apr 22, 2018·Journal of Invertebrate Pathology·Valluri V SatyavathiBernard Duvic
May 22, 2018·Journal of Visualized Experiments : JoVE·Jia-Hsin HuangHow-Jing Lee
Jul 1, 2018·Applied and Environmental Microbiology·Madhavi L KakumanuCoby Schal
Apr 10, 2019·Proceedings. Biological Sciences·Yudai NishideTakema Fukatsu
Feb 1, 1994·Journal of Food Protection·Robert J KopanicCharles G Wright

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

British Medical Journal
A E Shipley
British Medical Journal
A E Shipley
Transactions of the Royal Society of Tropical Medicine and Hygiene
M Stek
Anesthesia and Analgesia
John G Brock-Utne
Felʹdsher i akusherka
A A Odinets
© 2022 Meta ULC. All rights reserved