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The pH-dependence and group modification of beta-lactamase I

The Biochemical Journal

Sep 1, 1975

S G Waley

PMID: 996

Abstract

The pH-dependence of the kinetic parameters for the hydrolysis of the beta-lactam ring by beta-lactamase I (penicillinase, EC 3.5.2.6) was studied. Benzylpenicillin and ampicillin (6-[D(-)-alpha-aminophenylacetamido]penicillanic acid) were used. Both kcat. and kcat./Km for both substrat...read more

Mentioned in this Paper

beta-Lactams
Beta-Lactamase I
Imides
Soluble
Penicillinase
Hydrolase
Penicillanic Acid
Carboxylate
Exopenicillinase
Ukapen
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The pH-dependence and group modification of beta-lactamase I

The Biochemical Journal

Sep 1, 1975

S G Waley

PMID: 996

DOI:

Abstract

The pH-dependence of the kinetic parameters for the hydrolysis of the beta-lactam ring by beta-lactamase I (penicillinase, EC 3.5.2.6) was studied. Benzylpenicillin and ampicillin (6-[D(-)-alpha-aminophenylacetamido]penicillanic acid) were used. Both kcat. and kcat./Km for both substrat...read more

Mentioned in this Paper

beta-Lactams
Beta-Lactamase I
Imides
Soluble
Penicillinase
Hydrolase
Penicillanic Acid
Carboxylate
Exopenicillinase
Ukapen

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