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The pH-dependence and group modification of beta-lactamase I

The Biochemical Journal

Sep 1, 1975

S G. Waley

PMID: 996

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Abstract

The pH-dependence of the kinetic parameters for the hydrolysis of the beta-lactam ring by beta-lactamase I (penicillinase, EC 3.5.2.6) was studied. Benzylpenicillin and ampicillin (6-[D(-)-alpha-aminophenylacetamido]penicillanic acid) were used. Both kcat. and kcat./Km for both substrat...read more

Mentioned in this Paper

Soluble
Exopenicillinase
Hydrolase
Hydrolysis
Van-Pen-G
Imides
Ampicillin
Carboxyl Group
Beta-Lactamase I
Ukapen
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  • The pH-dependence and group modification of beta-lactamase I

    The Biochemical Journal

    Sep 1, 1975

    S G. Waley

    PMID: 996

    DOI:

    Abstract

    The pH-dependence of the kinetic parameters for the hydrolysis of the beta-lactam ring by beta-lactamase I (penicillinase, EC 3.5.2.6) was studied. Benzylpenicillin and ampicillin (6-[D(-)-alpha-aminophenylacetamido]penicillanic acid) were used. Both kcat. and kcat./Km for both substrat...read more

    Mentioned in this Paper

    Soluble
    Exopenicillinase
    Hydrolase
    Hydrolysis
    Van-Pen-G

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