PMID: 6807793Jul 1, 1982

The pH of ascitic fluid in the diagnosis of spontaneous bacterial peritonitis in alcoholic cirrhosis

Hepatology : Official Journal of the American Association for the Study of Liver Diseases
N GitlinR C Silvestri

Abstract

Fifty-six patients with alcoholic cirrhosis and ascites were studied. The ascitic fluid was analyzed for pH, PO2, PCO2 glucose, protein, specific gravity, amylase, lactic dehydrogenase, white blood cell count, polymorphonuclear count, and cytology. It was also cultured aerobically and anaerobically. Simultaneously, arterial blood was analyzed for pH, PO2, and PCO2. Venous blood was analyzed for complete blood count, protein, aspartate transaminase, and it was also cultured under aerobic and anaerobic conditions. Six patients had spontaneous bacterial peritonitis (SBP), i.e., culture was positive for Escherichia coli in five and Streptococcus faecalis in one. The mean (+/- S.E.) ascitic fluid pH in the SBP group wa 7.25 +/- 0.06 with a range of 7.12 to 7.31, while the ascitic fluid pH in the group with sterile ascites was 7.47 +/- 0.07 with a range of 7.39 to 7.58. The pH of the blood in both groups was 7.47 +/- 0.03. The pH of the ascites in the SBP group was significantly different from the pH in the group with sterile ascites, p less than 0.001. It was also significantly different from the blood pH, p less than 0.001. Highly significant inverse correlations existed between the ascitic pH in the SBP group and the ascitic white...Continue Reading

References

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Citations

May 1, 1990·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·N Gitlin
Jan 1, 1995·Scandinavian Journal of Gastroenterology·J L Sánchez-LombrañaL Rodrigo
Oct 26, 2013·Critical Reviews in Clinical Laboratory Sciences·Darci R Block, Alicia Algeciras-Schimnich
Apr 1, 1987·Scandinavian Journal of Gastroenterology·T Almdal, P Skinhøj
Jan 1, 1985·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·G Garcia-TsaoE Lerner
Mar 1, 1986·Infection·T AlmdalH Friis
Mar 1, 1986·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·G PinzelloL Pagliaro
Jul 1, 1990·Journal of Gastroenterology and Hepatology·J A Cuthbert
Jan 1, 1985·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·C Y YangI S Sheen
Jan 1, 1985·Alcoholism, Clinical and Experimental Research·D Frank, R F Raicht
Jan 1, 1988·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·B A Runyon
May 10, 2013·Microbial Ecology·Francesco CastellaniMaria M Lleo
Dec 1, 1988·European Journal of Clinical Investigation·K HuberB R Binder
Jul 1, 1982·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·H O CONN

Related Concepts

Peritoneal Fluid (Body Substance)
Bacterial Infections
Escherichia Coli Infections
Hydrogen-Ion Concentration
Differential White Blood Cell Count Procedure
Liver Cirrhosis, Alcoholic
Neutrophil Band Cells
Secondary Peritonitis
Streptococcal Infections
Enterococcus faecalis

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