The pharmacoeconomics of newer therapeutics for rheumatic diseases

Rheumatic Diseases Clinics of North America
Arthur Kavanaugh

Abstract

Rheumatic diseases are common, serious conditions characterized by alterations in normal immune homeostasis with resultant end-organ injury. Although diverse in clinical expression and pathophysiologic basis, therapeutic approaches for these conditions frequently overlap. Over the past decade, several important new therapies have been introduced into the clinic for the treatment of many rheumatic conditions. Although these agents have proven highly effective, their higher costs have raised questions concerning their most appropriate use in the clinic. This issue has been analyzed in greatest detail in rheumatoid arthritis. Increasing data suggest that newer therapeutics may be cost-effective for rheumatoid arthritis and other rheumatic diseases.

References

Feb 20, 1999·Arthritis and Rheumatism·G KobeltB Jönsson
May 20, 1999·Rheumatology·N P Hurst, J Forbes
Nov 30, 2000·The New England Journal of Medicine·P E LipskyUNKNOWN Anti-Tumor Necrosis Factor Trial in Rheumatoid Arthritis with Concomitant Therapy Study Group
Jun 16, 2001·Arthritis and Rheumatism·T PincusF Wolfe
Sep 19, 2001·Rheumatology·C M Lambert
Jan 16, 2003·Arthritis and Rheumatism·Sherine E GabrielEric L Matteson
Jan 16, 2003·Arthritis and Rheumatism·Tuulikki SokkaPekka Hannonen
Feb 13, 2003·Arthritis and Rheumatism·Cristina LajasJuan A Jover
Feb 13, 2003·Arthritis and Rheumatism·Dorothy D DunlopRowland W Chang
Oct 3, 2003·Rheumatology·F WolfeT Pincus
Mar 6, 2004·Lancet·Lars KlareskogUNKNOWN TEMPO (Trial of Etanercept and Methotrexate with Radiographic Patient Outcomes) study investigators
Mar 17, 2004·Annals of the Rheumatic Diseases·A MaetzelUNKNOWN Community Hypertension and Arthritis Project Study Team
Apr 13, 2004·Arthritis and Rheumatism·R N MainiUNKNOWN Anti-Tumor Necrosis Factor Trial in Rheumatoid Arthritis with Concomitant Therapy Study Group
Dec 14, 2004·Joint, Bone, Spine : Revue Du Rhumatisme·Anne-Christine Rat, Marie-Christophe Boissier
Feb 8, 2005·Arthritis and Rheumatism·Andreas Maetzel
Feb 11, 2005·The New England Journal of Medicine·Samuel A Bozzette
Apr 30, 2005·Annals of the Rheumatic Diseases·S M M VerstappenUNKNOWN Utrecht Rheumatoid Arthritis Cohort Study Group

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Citations

Oct 24, 2006·American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists·Burgunda V Sweet
Apr 7, 2007·Current Opinion in Rheumatology·Arthur Kavanaugh
Nov 18, 2014·Cadernos de saúde pública·Fabíola Bagatini BuendgensMareni Rocha Farias

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