The pharmacological activity of wheat bran polysaccharides

Fitoterapia
Lubica PrisenžňákováAnna Ebringerová

Abstract

(Glucurono)arabinoxylans were extracted from the wheat bran with acetate buffer in the first step (WBH1) and with dilute alkali in the second step (WBH2). In both samples xylose and arabinose dominated, accompanied with smaller amounts of galactose, glucose, mannose and uronic acids mainly in WBH1. WBH1 was free of protein and with low content of phenolic compounds. Fraction WBH2 contained relatively low levels of proteins and about 4.5% of the total phenolic. When tested for antitussive activity, the (glucurono)arabinoxylans exhibited comparable cough-suppressing effect with centrally acting codeine. The observed effects of bronchoconstriction are limiting practical application of WBH2.

References

Jun 1, 1990·Thorax·R W Fuller, D M Jackson
Oct 3, 2002·Journal of Agricultural and Food Chemistry·Kafui Kwami Adom, Rui Hai Liu
May 3, 2003·Ultrasonics Sonochemistry·Z Hromádková, A Ebringerová
May 13, 2003·The Proceedings of the Nutrition Society·Joanne Slavin
Jun 18, 2003·Current Opinion in Pharmacology·Maria G Belvisi
Oct 11, 2003·Biotechnology Advances·S R Rao, G A Ravishankar
Oct 17, 2003·Current Drug Targets. Inflammation and Allergy·G BochenekA Szczeklik
Mar 26, 2004·European Journal of Clinical Nutrition·Z X LuK O'Dea
Jan 13, 2006·Respiratory Physiology & Neurobiology·Peter V Dicpinigaitis
May 8, 2007·Biophysical Journal·Trushar R PatelArthur J Rowe
Jun 1, 2000·Nutrition Research Reviews·R B WillsM Morgan
Jan 20, 2009·International Journal of Biological Macromolecules·M SutovskáP Capek
Oct 16, 2009·Lung·Sarah A Maher, Maria G Belvisi

❮ Previous
Next ❯

Citations

Oct 17, 2012·Journal of Agricultural and Food Chemistry·Lauri PolariSeppo Salminen
Apr 3, 2012·Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy·A Pielesz
Oct 9, 2012·International Journal of Biological Macromolecules·M ŠutovskáR Gancarz
Dec 22, 2019·Biomolecules·Agne KatileviciuteRimantas Kodzius

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.