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The pharmacology of adrenergic neuronal responses in the cerebral cortex: evidence for excitatory alpha- and inhibitory beta-receptors

British Journal of Pharmacology

Apr 1, 1977

Paul BevanElemér Szabadi

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Abstract

1. The technique of microelectrophoresis was used to compare the actions of a range of adrenoceptor agonists on single cortical neurones in the rat anaesthetized with halothane. 2. Phenylephrine and methoxamine were exclusively excitatory, whereas salbutamol was entirely depressant. Nor...read more

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Acetylcholine Measurement
Propranolol
Receptors, Adrenergic, beta-1
Norepinephrine
Methoxamine
Agonists
Metazoa
Insula of Reil
Beta-adrenergic receptor
Adrenergic alpha-Antagonists
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  • The pharmacology of adrenergic neuronal responses in the cerebral cortex: evidence for excitatory alpha- and inhibitory beta-receptors

    British Journal of Pharmacology

    Apr 1, 1977

    Paul BevanElemér Szabadi

    PMID: 15697

    DOI: 10.1111/j.1476-5381.1977.tb07732.x

    Abstract

    1. The technique of microelectrophoresis was used to compare the actions of a range of adrenoceptor agonists on single cortical neurones in the rat anaesthetized with halothane. 2. Phenylephrine and methoxamine were exclusively excitatory, whereas salbutamol was entirely depressant. Nor...read more

    Mentioned in this Paper

    Acetylcholine Measurement
    Propranolol
    Receptors, Adrenergic, beta-1
    Norepinephrine
    Methoxamine

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