No abstract listed.
Comparison of the effects of nine beta-adrenergic blocking agents on intraocular pressure in rabbits
Localization of beta-andrenoceptors in the anterior segment of the albino rabbit eye using a fluorescent analog of propranolol
The influence of clonidine on intraocular pressure after topical application to the eyes of anesthetized cats
Cannabinoid action on the eye as mediated through the central nervous system and local adrenergic activity
Effects of S-596 and carteolol, new beta-adrenergic blockers, and flurbiprofen on the human eye: a fluorophotometric study
Ocular hypotensive effect of marihuana cannabinoids: correlate of central action or separate phenomenon?
Comparative effects of SCH 19927 and timolol on intraocular pressure of conscious rabbits and relative systemic beta-blockade resulting from topical administration
Effects of the beta 2-adrenoceptor antagonist ICI 118,551 on exercise tachycardia and isoprenaline-induced beta-adrenoceptor responses in man
Alpha-adrenergic antagonists: correlation of the effect on intraocular pressure and on alpha 2-adrenergic receptor binding specificity in the rabbit eye
Bronchial beta-adrenoceptor blockade following eyedrops of timolol and its isomer L-714,465 in normal subjects
A blind randomised cross-over trial comparing metipranolol 0.3% with timolol 0.25% in open-angle glaucoma: a pilot study
Pharmacological characterization of beta-adrenoceptor subtype involvement in the ocular hypotensive response to beta-adrenergic stimulation
Synthesis of a series of compounds related to betaxolol, a new beta 1-adrenoceptor antagonist with a pharmacological and pharmacokinetic profile optimized for the treatment of chronic cardiovascular diseases
Ocular levobunolol. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy
Does B-HT 920 lower intraocular pressure in cats by interacting with alpha 2- and/or DA2 adrenoceptors?
Adrenergic receptor subtypes in rabbit iris-ciliary body membranes: classification by radioligand studies
ATPases of ciliary epithelium: cellular and subcellular distribution and probable role in secretion of aqueous humor
Evidence that the alpha and alpha (+)isoforms of the catalytic subunit of (Na+, K+)-ATPase reside in distinct ciliary epithelial cells of the mammalian eye
An elucidation of the arachidonic acid cascade. Discovery of prostaglandins, thromboxane and leukotrienes
Systemic effects resulting from topical ocular administration of SCH 33861, a novel ACE inhibitor ocular hypotensive agent
A double-crossover trial comparing the effects of topical carteolol and placebo on intraocular pressure
A single-blind randomised trial comparing adrenaline 1.0% with dipivalyl epinephrine (propine) 0.1% in the treatment of open-angle glaucoma and ocular hypertension
A study of the effects of four concentrations of D-timolol, 0.25% L-timolol, and placebo on intraocular pressure on patients with raised intraocular pressure
Effects of L-timolol, D-timolol, haloperidol and domperidone on rabbit retinal blood flow measured with laser Doppler method
Prostaglandin F2 alpha-1-isopropylester lowers intraocular pressure without decreasing aqueous humor flow
Relative effectiveness of prodrug and viscous solution approaches in maximizing the ratio of ocular to systemic absorption of topically applied timolol
Effects of intracamerally infused prostaglandins on outflow facility in cynomolgus monkey eyes with intact or retrodisplaced ciliary muscle
Ocular penetration and hypotensive activity of the topically applied carbonic anhydrase inhibitor L-645,151
Nasal and conjunctival contributions to the systemic absorption of topical timolol in the pigmented rabbit: implications in the design of strategies to maximize the ratio of ocular to systemic absorption
Topical ocular hypotensive effects of the novel angiotensin converting enzyme inhibitor SCH 33861 in conscious rabbits
Cianergoline lowers intraocular pressure in rabbits and monkeys and inhibits contraction of the cat nictitans by suppressing sympathetic neuronal function
Histochemistry of adenylate cyclase activity in the anterior segment of the eye: a methodological evaluation with biochemical background
Eicosanoids as a new class of ocular hypotensive agents. 1. The apparent therapeutic advantages of derived prostaglandins of the A and B type as compared with primary prostaglandins of the E, F and D type
Effects of vasoactive intestinal polypeptide (VIP) on intraocular pressure, facility of outflow and formation of aqueous humor in the monkey
Topical carbonic anhydrase inhibitors. III: Optimization model for corneal penetration of ethoxzolamide analogues
Ocular hypotension, ocular toxicity, and neurotoxicity in response to marihuana extract and cannabidiol
The effects of adrenergic agonists and antagonists on the adenylate cyclase in albino rabbit ciliary processes
Effects of adrenergic agonists upon regional ocular blood flow in normal and ganglionectomized rabbits
The effect of selective alpha 1- and alpha 2-adrenoceptor stimulation on intraocular pressure in the conscious rabbit
Role of the beta-adrenergic receptor-binding agent 'timolol' in the treatment of open-angle glaucoma
Use of (S)-(trifloxymethyl)oxirane in the synthesis of a chiral beta-adrenoceptor antagonist, (R)- and (S)-9-[[3-(tert-butylamino)-2-hydroxypropyl]oximino]fluorene
6-Chloro-2,3,4,5-tetrahydro-3-methyl-1H-3-benzazepine: a potent and selective antagonist of alpha 2-adrenoceptors
Shortterm "escape" and longterm "drift." The dissipation effects of the beta adrenergic blocking agents
Binding potencies of 3 new beta 2 specific blockers to beta receptors in the ciliary processes and the possible relevance of these drugs to intraocular pressure control
Atrial natriuretic factor elicits an endothelium-independent relaxation and activates particulate guanylate cyclase in vascular smooth muscle
ICI 118,551: an effective ocular hypotensive agent with selectivity for the ciliary process beta 2-adrenoceptor and with minimal cardiac side effects
Possible alpha-adrenoceptor blocking activity of arotinolol (S-596), a new beta-adrenoceptor blocking agent in isolated dog coronary artery
Adrenergic regulation of intraocular pressure: identification of beta 2-adrenergic-stimulated adenylate cyclase in ciliary process epithelium
The effects of topically applied epinephrine and timolol on intraocular pressure and aqueous humor cyclic-AMP in the rabbit
Effect of pindolol on intraocular pressure in glaucoma: pilot study and a randomised comparison with timolol
Immunohistochemical demonstration of carbonic anhydrase isoenzyme C in the epithelium of the human ciliary processes
The general physiology of reactions catalyzed by carbonic anhydrase and their inhibition by sulfonamides
Intraocular pressure, ocular toxicity and neurotoxicity after administration of cannabinol or cannabigerol
Combined effect of forskolin and acetazolamide on intraocular pressure and aqueous flow in rabbit eyes
Disposition of ophthalmic timolol in treated and untreated rabbit eyes. A multiple and single dose study
Immunohistochemical and biochemical evidence for 5-hydroxytryptamine containing nerves in the anterior part of the eye
The effect of topically administered carbonic anhydrase inhibitors on aqueous humor dynamics in rabbits
The transcorneal permeability of sulfonamide carbonic anhydrase inhibitors and their effect on aqueous humor secretion
The aqueous humor dynamics and the biphasic response in intraocular pressure induced by guanethidine and adrenaline in the glaucomatous eye
Continuous, simultaneous, and instant display of aqueous humor dynamics with a micro-spectrophotometer and a sensitive drop counter
Cardiovascular effects of epinephrine and dipivalyl epinephrine applied topically to the eye in patients with glaucoma
Synthesis of cyclooxygenase products by human anterior uvea from cyclic prostaglandin endoperoxide (PGH2)
The effects of topical prazosin on normal and elevated intraocular pressure and blood pressure in rabbits
Improvement of the co-efficient of outflow in glaucomatous eyes. Prolonged local treatment with epinephrine
ANGIOTENSIN AND RENAL NA-K ACTIVATED ADENOSINE TRIPHOSPHATASE. (STUDIES ON NA-K ACTIVATED ATPASE, VIII)
Effects of topical natural ergot alkaloids on intraocular pressure and aqueous humor dynamics in ocular normotensive rabbits
L-662,583 is a topically effective ocular hypotensive carbonic anhydrase inhibitor in experimental animals
Acetazolamide-induced cilio-choroidal effusion after cataract surgery: unusual posterior involvement
A comparison of L-671,152 and MK-927, two topically effective ocular hypotensive carbonic anhydrase inhibitors, in experimental animals
Cyclodextrin complexes of sulfonamide carbonic anhydrase inhibitors as long-lasting topically acting antiglaucoma agents
Development of eye drops containing antihypertensive drugs: formulation of aqueous irbesartan/γCD eye drops
Topically applied betaxolol attenuates NMDA-induced toxicity to ganglion cells and the effects of ischaemia to the retina
Monothiocarbamates Strongly Inhibit Carbonic Anhydrases in Vitro and Possess Intraocular Pressure Lowering Activity in an Animal Model of Glaucoma
Ocular Drug Delivery Barriers-Role of Nanocarriers in the Treatment of Anterior Segment Ocular Diseases
Pharmacological and pharmacokinetic profile of the novel ocular hypotensive prodrug CKLP1 in Dutch-belted pigmented rabbits
A review of nanocarrier-mediated drug delivery systems for posterior segment eye disease: challenges analysis and recent advances.
Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.
Chronic Fatigue Syndrome
Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.
Systemic Juvenile Idiopathic Arthritis
Systemic juvenile idiopathic arthritis is a rare rheumatic disease that affects children. Symptoms include joint pain, but also fevers and skin rashes. Here is the latest on this disease.
Chromatin Regulation and Circadian Clocks
The circadian clock plays an important role in regulating transcriptional dynamics through changes in chromatin folding and remodelling. Discover the latest research on Chromatin Regulation and Circadian Clocks here.
Central Pontine Myelinolysis
Central Pontine Myelinolysis is a neurologic disorder caused most frequently by rapid correction of hyponatremia and is characterized by demyelination that affects the central portion of the base of the pons. Here is the latest research on this disease.
Myocardial stunning is a mechanical dysfunction that persists after reperfusion of previously ischemic tissue in the absence of irreversible damage including myocardial necrosis. Here is the latest research.
Pontocerebellar hypoplasias are a group of neurodegenerative autosomal recessive disorders with prenatal onset, atrophy or hypoplasia of the cerebellum, hypoplasia of the ventral pons, microcephaly, variable neocortical atrophy and severe mental and motor impairments. Here is the latest research on pontocerebellar hypoplasia.
Cell Atlas Along the Gut-Brain Axis
Profiling cells along the gut-brain axis at the single cell level will provide unique information for each cell type, a three-dimensional map of how cell types work together to form tissues, and insights into how changes in the map underlie health and disease of the GI system and its crosstalk with the brain. Disocver the latest research on single cell analysis of the gut-brain axis here.
Chronic Traumatic Encephalopathy
Chronic Traumatic Encephalopathy (CTE) is a progressive degenerative disease that occurs in individuals that suffer repetitive brain trauma. Discover the latest research on traumatic encephalopathy here.