PMID: 9434851Jan 22, 1998Paper

The photogenotoxicity of titanium dioxide particles

Mutation Research
Y NakagawaN Tanaka

Abstract

We employed a series of in vitro genotoxicity assays--a single cell gel (SCG) assay with mouse lymphoma L5178Y cells, a microbial mutation assay with Salmonella typhimurium, a mammalian cell mutation assay with L5178Y cells, and a chromosomal aberration assay with Chinese hamster CHL/IU cells--to evaluate the photogenotoxicity of titanium dioxide (TiO2) particles. Without UV/visible light irradiation, TiO2 particles exhibited no or weak genotoxicity. With irradiation, however, TiO2 particles exhibited significant genotoxicity in the SCG and chromosomal aberration assays. Therefore, we concluded that TiO2 particles are photogenotoxic.

References

Apr 1, 1990·American Journal of Respiratory Cell and Molecular Biology·K E DriscollG Ridder
Mar 1, 1988·Experimental Cell Research·N P SinghE L Schneider
Jun 30, 1985·Toxicology and Applied Pharmacology·K P LeeC F Reinhardt
May 1, 1983·Mutation Research·D M Maron, B N Ames
Feb 1, 1995·American Journal of Respiratory Cell and Molecular Biology·R M SchapiraA D Hacker
Jan 1, 1993·Environmental and Molecular Mutagenesis·M D ShelbyR R Tice
Aug 1, 1994·Toxicology in Vitro : an International Journal Published in Association with BIBRA·H SpielmannA Willshaw

❮ Previous
Next ❯

Citations

Mar 30, 2012·Archives of Toxicology·Franz Oesch, Robert Landsiedel
Aug 14, 2012·Archives of Toxicology·Sijing XiongSay Chye Joachim Loo
Jun 22, 2010·Analytical and Bioanalytical Chemistry·Elijah J Petersen, Bryant C Nelson
Jul 20, 2010·Analytical and Bioanalytical Chemistry·Hanna L Karlsson
Aug 13, 2011·Archives of Dermatological Research·Dimitrios PapakostasAnnika Vogt
Jan 19, 2013·Bulletin of Experimental Biology and Medicine·G E OnishchenkoV A Tutelyan
Jun 2, 2005·Journal of the American Academy of Dermatology·Prisana Kullavanijaya, Henry W Lim
May 26, 2005·Toxicology and Applied Pharmacology·Neera V GopeePaul C Howard
Feb 7, 2001·Mutation Research·T AshikagaT Takamatsu
Jan 7, 2004·Mutation Research·Susanne Brendler-SchwaabDietmar Utesch
Mar 10, 2009·Toxicological Sciences : an Official Journal of the Society of Toxicology·Timothy R NurkiewiczVincent Castranova
Jul 12, 2012·Photochemistry and Photobiology·Jean CadetThierry Douki
Aug 3, 2002·Environmental Health Perspectives·Qamar RahmanDietmar Schiffmann
Jun 26, 2012·Arhiv za higijenu rada i toksikologiju·Katharina Klien, Jasminka Godnić-Cvar
Apr 29, 2014·Mutation Research. Genetic Toxicology and Environmental Mutagenesis·Kimberly S ButlerRosalie K Elespuru
Aug 19, 2014·Toxicological Sciences : an Official Journal of the Society of Toxicology·Akmal A El-GhorHanan Ramadan H Mohamed
Mar 15, 2014·Anais Brasileiros De Dermatologia·João Roberto AntonioJoão Rodrigo Oliveira
Aug 14, 2010·Toxicological Sciences : an Official Journal of the Society of Toxicology·Brian GulsonGavin Greenoak
Apr 25, 2007·Critical Reviews in Toxicology·Gerhard J NohynekMichael S Roberts
Nov 19, 2013·Journal of the American Academy of Dermatology·Rebecca JansenHenry W Lim
Feb 24, 2015·Environment International·Denise M MitranoBernd Nowack
Feb 19, 2013·Mutation Research·Lutz Müller, Elmar Gocke
Nov 26, 2011·Toxicology and Applied Pharmacology·Kristen SandersWilliam K Boyes
Nov 30, 2011·Seminars in Cutaneous Medicine and Surgery·Steven Q Wang, Ian R Tooley
Mar 30, 2010·Experimental and Toxicologic Pathology : Official Journal of the Gesellschaft Für Toxikologische Pathologie·Hasan Turkez
Jan 6, 2012·The Journal of Investigative Dermatology·Lisa A DeLouise
Oct 23, 2008·Clinics in Dermatology·Salvador GonzálezYolanda Gilaberte-Calzada
Sep 15, 2007·Mutation Research·Elizabeth TheogarajDavid Kirkland
Jun 30, 2012·Journal of Applied Toxicology : JAT·Robert S WoodruffTao Chen
Jul 26, 2011·Environmental and Molecular Mutagenesis·Shuguang WangJeffrey K Wickliffe
Mar 12, 2011·Photodermatology, Photoimmunology & Photomedicine·Mark E Burnett, Steven Q Wang
Feb 9, 2010·Dermatologic Therapy·Steven Q WangUli Osterwalder
Sep 17, 2013·Skin Research and Technology : Official Journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)·F RancanM C Meinke

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.