The PHQ-9: validity of a brief depression severity measure

Journal of General Internal Medicine
K KroenkeJ B Williams

Abstract

While considerable attention has focused on improving the detection of depression, assessment of severity is also important in guiding treatment decisions. Therefore, we examined the validity of a brief, new measure of depression severity. The Patient Health Questionnaire (PHQ) is a self-administered version of the PRIME-MD diagnostic instrument for common mental disorders. The PHQ-9 is the depression module, which scores each of the 9 DSM-IV criteria as "0" (not at all) to "3" (nearly every day). The PHQ-9 was completed by 6,000 patients in 8 primary care clinics and 7 obstetrics-gynecology clinics. Construct validity was assessed using the 20-item Short-Form General Health Survey, self-reported sick days and clinic visits, and symptom-related difficulty. Criterion validity was assessed against an independent structured mental health professional (MHP) interview in a sample of 580 patients. As PHQ-9 depression severity increased, there was a substantial decrease in functional status on all 6 SF-20 subscales. Also, symptom-related difficulty, sick days, and health care utilization increased. Using the MHP reinterview as the criterion standard, a PHQ-9 score > or =10 had a sensitivity of 88% and a specificity of 88% for major de...Continue Reading

Associated Clinical Trials

Jul 6, 2016·Kerry E. Evers
Mar 1, 2017·Derek Richards

References

Apr 1, 1979·The British Journal of Psychiatry : the Journal of Mental Science·S A Montgomery, M Asberg
Feb 11, 1991·Medical Care·D M BerwickM C Weinstein
Mar 1, 1989·Medical Care·L E KazisR F Meenan
May 1, 1986·Acta Psychiatrica Scandinavica·J DavidsonK Graves
Jun 15, 1995·Annals of Internal Medicine·C D MulrowC Kerber
Oct 1, 1996·Archives of General Psychiatry·W KatonE Walker
Jul 1, 1997·Journal of General Internal Medicine·M A WhooleyW S Browner
Dec 1, 1998·JAMA : the Journal of the American Medical Association·M B KellerW Harrison
May 13, 1999·The American Journal of Medicine·J W WilliamsS Lee
Sep 23, 2000·JAMA : the Journal of the American Medical Association·J W WilliamsA Sengupta

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Citations

Jul 10, 2004·Journal of General Internal Medicine·Teri GrecoKurt Kroenke
Jan 12, 2005·The Diabetes Educator·Lonnie K WenMichael L Parchman
Dec 22, 2004·Journal of General Internal Medicine·Russell E GlasgowHilarea Amthauer
Apr 30, 2005·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Kathleen EllChristy Russell
Mar 24, 2005·Psychosomatic Medicine·Michael Von KorffTerry Bush
Jan 29, 2005·Stroke; a Journal of Cerebral Circulation·Linda S WilliamsKurt Kroenke
Oct 11, 2005·Administration and Policy in Mental Health·Bruce L RollmanHerbert C Schulberg
Jun 21, 2005·Journal of General Internal Medicine·Raz GrossMyrna M Weissman
Jul 30, 2005·Journal of General Internal Medicine·Alejandra Pinto-MezaJosep Maria Haro
Jun 25, 2005·Mental Health Services Research·Kathryn RostRichard C Hermann
Jul 28, 2005·Alcoholism, Clinical and Experimental Research·R Scott BraithwaiteAmy C Justice
Aug 4, 2005·Annals of Clinical Psychiatry : Official Journal of the American Academy of Clinical Psychiatrists·Usman HameedFrancesca Bertone
Jan 21, 2006·Rehabilitation Nursing : the Official Journal of the Association of Rehabilitation Nurses·Tamilyn BakasLinda S Williams
Jan 21, 2006·Journal of General Internal Medicine·David W OslinIra R Katz
Nov 15, 2005·AIDS·Sanjay BasuR Douglas Bruce
Dec 13, 2005·Nephron. Clinical Practice·Michelle C OddenMichael G Shlipak
Jul 1, 2006·Journal of General Internal Medicine·Frederick Y HuangRobert L Spitzer
Aug 16, 2006·BMC Family Practice·Nancy S MorrisBenjamin Littenberg
Sep 19, 2006·Nursing Research·Tamilyn BakasLinda S Williams
Aug 2, 2006·Journal of General Internal Medicine·Margaret ShihTeresa J Brady
Sep 7, 2006·International Journal of Geriatric Psychiatry·Albert YeungMaurizio Fava
Dec 13, 2006·Harvard Review of Psychiatry·Jeff C HuffmanGregory L Fricchione
Apr 26, 2007·Clinical Trials : Journal of the Society for Clinical Trials·Miles McFallPhilip W Lavori
Mar 3, 2007·Clinical Rheumatology·Thomas RosemannJoachim Szecsenyi
Feb 10, 2007·Psychosomatic Medicine·Lisa C BarryHarlan M Krumholz
Aug 1, 2007·Arthritis and Rheumatism·Brett D ThombsMurray Baron
May 24, 2007·AIDS Patient Care and STDs·Faika ZanjaniDavid Oslin
May 23, 2007·The Clinical Journal of Pain·Marieke M WollaarsNico Brand
Aug 10, 2007·Current Pain and Headache Reports·Karen O Anderson
Sep 7, 2007·Psychological Medicine·D A RichardsR Richardson
Oct 16, 2007·Digestive Diseases and Sciences·Nader DboukAasim Sheikh
Jan 9, 2008·Evaluation & the Health Professions·Roger A BoothroydHuey Jen Chen
Dec 6, 2007·Expert Review of Neurotherapeutics·Jeanne Leventhal AlexanderEnid M Hunkeler
May 6, 2008·Maternal and Child Health Journal·Patricia A Harrison, Abbey C Sidebottom
Dec 29, 2007·The American Journal of Drug and Alcohol Abuse·Jennifer S PotterRoger D Weiss
Sep 18, 2007·Journal of General Internal Medicine·Simon GilbodyCatherine Hewitt

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