The physical significance of acoustic parameters and its clinical significance of dysarthria in Parkinson's disease.

Scientific Reports
Shu YangXianwei Zou

Abstract

Dysarthria is universal in Parkinson's disease (PD) during disease progression; however, the quality of vocalization changes is often ignored. Furthermore, the role of changes in the acoustic parameters of phonation in PD patients remains unclear. We recruited 35 PD patients and 26 healthy controls to perform single, double, and multiple syllable tests. A logistic regression was performed to differentiate between protective and risk factors among the acoustic parameters. The results indicated that the mean f0, max f0, min f0, jitter, duration of speech and median intensity of speaking for the PD patients were significantly different from those of the healthy controls. These results reveal some promising indicators of dysarthric symptoms consisting of acoustic parameters, and they strengthen our understanding about the significance of changes in phonation by PD patients, which may accelerate the discovery of novel PD biomarkers.

References

Aug 1, 1991·Journal of Communication Disorders·P ZwirnerG E Woodson
Jun 1, 1969·Journal of Speech and Hearing Research·F L DarleyJ R Brown
Jun 1, 1982·The Journal of the Acoustical Society of America·E YumotoT Baer
Sep 23, 1997·Journal of Voice : Official Journal of the Voice Foundation·J GamboaI Cobeta
Oct 3, 1999·Journal of Telemedicine and Telecare·C RuggieroM Giacomini
Jan 6, 2000·Journal of Voice : Official Journal of the Voice Foundation·J JiangD Hanson
Aug 30, 2000·International Journal of Language & Communication Disorders·R J HolmesA J Hughes
Jun 18, 2002·Journal of Communication Disorders·Alexander GobermanMichael Robb
Jul 13, 2002·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·A V YücetürkS Karaca
Mar 7, 2003·Movement Disorders : Official Journal of the Movement Disorder Society·Mark GuttmanC David Naylor
Jan 5, 2005·The Laryngoscope·Teofilo C Gozaine, Keith F Clark
Jul 11, 2006·The Laryngoscope·Paul K Y LamWilliam I Wei
Jul 31, 2007·Journal of Voice : Official Journal of the Voice Foundation·Christopher DromeyJ Arden Hopkin
Mar 15, 2008·Experimental Brain Research·Charles R LarsonTimothy C Hain
Apr 3, 2008·Movement Disorders : Official Journal of the Movement Disorder Society·Sabine Skodda, Uwe Schlegel
Jan 2, 2009·Movement Disorders : Official Journal of the Movement Disorder Society·Sabine SkoddaUwe Schlegel
Aug 15, 2009·Journal of Neural Transmission·Matthias LöhleHeinz Reichmann
Apr 1, 2009·IEEE Transactions on Bio-medical Engineering·Max A LittleLorraine O Ramig
Sep 20, 2012·Arquivos de neuro-psiquiatria·Luiza Furtado e SilvaIara Barreto Bassi
May 8, 2013·NeuroRehabilitation·Young-Im BangSung-Rae Cho
Sep 26, 2014·Current Opinion in Otolaryngology & Head and Neck Surgery·Jack J Jiang, Allison L Maytag
Nov 11, 2014·Computer Speech & Language·Alireza BayestehtashkJames McNames
Mar 22, 2015·Journal of Voice : Official Journal of the Voice Foundation·Yukiko IkuiFumiaki Tanaka
Sep 26, 2015·Journal of Parkinson's Disease·Alice K SilbergleitGlendon M Gardner
Nov 30, 2015·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Giovanni DefazioVincenzo di Nicola
Jan 5, 2016·Journal of Voice : Official Journal of the Voice Foundation·Fatemeh MajdinasabGholamali Shahidi
Feb 2, 2016·Computer Methods and Programs in Biomedicine·Zoltan GalazDagmar Berankova
Feb 24, 2016·Current Opinion in Otolaryngology & Head and Neck Surgery·Patricia Gillivan-MurphyNick Miller
Mar 12, 2016·Reviews in the Neurosciences·Jacob J CrouseAhmed A Moustafa
Mar 16, 2016·PloS One·Ruth Gil-PrietoAngel Gil-de-Miguel
Sep 29, 2017·Annals of Agricultural and Environmental Medicine : AAEM·Józef OparaTeresa Socha
Nov 6, 2017·Mayo Clinic Proceedings·Erik K St Louis, Bradley F Boeve
May 26, 2018·Journal of Speech, Language, and Hearing Research : JSLHR·Defne AburCara E Stepp
May 6, 2019·Journal of Neurology·Theresita JosephAlastair J Noyce
Dec 12, 2019·Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova·A P ArefyevaE E Vasenina
Mar 24, 2020·Journal of Voice : Official Journal of the Voice Foundation·Joice Maely Souza da SilvaZulina Souza de Lira

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Citations

Mar 9, 2021·Neural Networks : the Official Journal of the International Neural Network Society·Siddhant GuptaRodrigo Capobianco Guido
May 19, 2021·Journal of the Neurological Sciences·Pawichaya SuphinnapongRoongroj Bhidayasiri
Nov 11, 2021·CNS Neuroscience & Therapeutics·Jingsheng YangFan Xu

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