The phytochemistry, pharmacokinetics, pharmacology and toxicity of Euphorbia semen

Journal of Ethnopharmacology
An ZhuQi Wang

Abstract

Euphorbia semen, the dried and ripe seed of Euphorbia lathyris Linnaeus, is widely cultivated for traditional medicine use. This semen is used to expel water, help with phlegm retention, promote blood circulation, remove blood stasis, cure tinea and scabies, and treat amenorrhea, snakebites, terminal schistosomiasis, anuria and constipation. This review provides updated, comprehensive and categorized information on the local and traditional uses, phytochemistry, pharmacokinetics, pharmacological activities and toxicity of Euphorbia semen. Future research to deepen the recognition and utilization of Euphorbia semen is proposed. This article conducted a literature review on information about Euphorbia semen in multiple Internet databases, including PubMed, Web of Science, Wiley, Science Direct, Elsevier, ACS publications, SciFinder, Google Scholar and China National Knowledge Internet, until March of 2018. In this manuscript, a number of books, PhD and MSc dissertations, and Chinese Pharmacopeia were also used as references. Approximately 240 chemical constituents have been isolated and identified from Euphorbia semen, namely, diterpenoids, coumarins, flavonoids, fatty acids, amino acids, and steroids. Pharmacokinetic study focus...Continue Reading

Citations

Jul 30, 2020·Journal of Ethnopharmacology·Yaoqi LiuJiali Zhang
Oct 28, 2019·Phytomedicine : International Journal of Phytotherapy and Phytopharmacology·An ZhuQi Wang
Mar 1, 2019·Journal of Natural Products·Cui-Yun ZhangLi-Xia Chen
Aug 28, 2021·Evidence-based Complementary and Alternative Medicine : ECAM·Hui-Nan WangYing-Zi Wang

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