PMID: 746543Jan 1, 1978Paper

The pituitary cleft of the rat: an electron microscopic study

Tissue & Cell
D R Ciocca, C B González

Abstract

The epithelium of the pituitary cleft and its colloid have been studied at the ultrastructural level in normal, adrenalectomized, castrated, dehydrated and lactating adult rats. Both control and experimental animals showed cells in different stages of degradation inside the cleft and mixed with the colloid. These exfoliated cells seems to have originated from the cleft's epithelium of the adjacent granular cells. In adrenalectomized and castrated rats the rostral epithelium of the cleft had large intercellular spaces that in some instances appeared to open directly into the cleft. Occasionally, the adenohypophysial canaliculi of the adrenalectomized rats were also seen connecting with the cleft. In lactating and castrated animals dark cells appeared more frequently in the rostral and caudal epithelium of the cleft. The results obtained suggest that the colloids is originated at least in part by involuted pituitary cells. There is also evidence that the follicular cavities of the Pars distalis and the cleft are continuous structures.

References

Apr 7, 1977·Cell and Tissue Research·R C Santolaya, E M Rodríguez
Jan 1, 1970·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·P K Nakane
Jan 1, 1970·Zeitschrift für Zellforschung und mikroskopische Anatomie·T Vanha-Perttula, A U Arstila
Jan 1, 1972·Zeitschrift für Zellforschung und mikroskopische Anatomie·K P Dingemans, C A Feltkamp
Jan 1, 1969·Zeitschrift Für Anatomie Und Entwicklungsgeschichte·M Sano, F Sasaki
Feb 1, 1969·General and Comparative Endocrinology·S K Masur

Citations

Oct 12, 2012·PloS One·J Patrizia StohnVolkhard Lindner
Jul 8, 2003·The Anatomical Record. Part A, Discoveries in Molecular, Cellular, and Evolutionary Biology·Giacomo AzzaliGiuseppina Romita
Jul 8, 2008·Journal of Neuroendocrinology·S Devnath, K Inoue
Dec 1, 1981·General and Comparative Endocrinology·M Benjamin
May 1, 1988·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·F Harrisson
Jan 1, 1987·Virchows Archiv. A, Pathological Anatomy and Histopathology·G Gon

Related Concepts

Adrenalectomy
Castration
Protoplasm
Cytoplasmic Granules
Mesothelium
Extracellular Space
Lactation, Prolonged
Organoids
Pituitary Stalk

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