PMID: 3759531Oct 1, 1986Paper

The place of brachytherapy in the treatment of carcinoma of the tonsil with lingual extension

International Journal of Radiation Oncology, Biology, Physics
J H LeborgneB Ortega

Abstract

One hundred forty-four of 170 patients (85%) were seen with cancer of the tonsil and received radical irradiation between 1959 and 1980. A 39% crude 3-year disease-free survival rate and a 51% locoregional control rate were observed. Locoregional relapse related to T Stage was 6, 43, 58, and 64% for T1, T2, T3, and T4, respectively. Fifty-four of 144 patients (37%) showed tongue extension, 20% in T1-T2 stages and 50% in T3-T4 stages. Local relapse was 64% and the 3-year disease-free survival rate was 23% in 39 patients with tongue extension treated with external irradiation alone, versus 33 and 43% respectively for 90 patients with no tongue extension. The increase of lymph node metastases or neck recurrences was not related to tongue extension. In 15 patients with tongue extension, treated with external radiation plus brachytherapy, the local relapse was 40% and the 3-year survival rate 60%. External irradiation plus brachytherapy was significantly related to lower local relapse and increased survival rate compared to external irradiation alone in cancer of the tonsil with tongue extension. The combined modality was not associated with increased risk of radiation complications.

References

Jan 1, 1977·International Journal of Radiation Oncology, Biology, Physics·D R GoffinetM A Bagshaw
Feb 1, 1977·Cancer·F Cardinale, J J Fischer
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Citations

May 14, 2005·International Journal of Radiation Oncology, Biology, Physics·Jerry D SlaterJames M Slater
Oct 30, 2009·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Missak HaigentzAlfio Ferlito
Jan 1, 1992·International Journal of Radiation Oncology, Biology, Physics·J M SlaterJ O Archambeau
Sep 30, 1993·International Journal of Radiation Oncology, Biology, Physics·J J MazeronR Peynegre

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