The plastidial metabolite 2-C-methyl-D-erythritol-2,4-cyclodiphosphate modulates defence responses against aphids

Plant, Cell & Environment
Nawaporn OnkokesungMarcel Dicke

Abstract

Feeding by insect herbivores such as caterpillars and aphids induces plant resistance mechanisms that are mediated by the phytohormones jasmonic acid (JA) and salicylic acid (SA). These phytohormonal pathways often crosstalk. Besides phytohormones, methyl-D-erythriol-2,4-cyclodiphosphate (MEcPP), the penultimate metabolite in the methyl-D-erythritol-4-phosphate pathway, has been speculated to regulate transcription of nuclear genes in response to biotic stressors such as aphids. Here, we show that MEcPP uniquely enhances the SA pathway without attenuating the JA pathway. Arabidopsis mutant plants that accumulate high levels of MEcPP (hds3) are highly resistant to the cabbage aphid (Brevicoryne brassicae), whereas resistance to the large cabbage white caterpillar (Pieris brassicae) remains unaltered. Thus, MEcPP is a distinct signalling molecule that acts beyond phytohormonal crosstalk to induce resistance against the cabbage aphid in Arabidopsis. We dissect the molecular mechanisms of MEcPP mediating plant resistance against the aphid B. brassicae. This shows that MEcPP induces the expression of genes encoding enzymes involved in the biosynthesis of several primary and secondary metabolic pathways contributing to enhanced resis...Continue Reading

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Citations

Nov 10, 2020·Frontiers in Plant Science·Erica PerrecaLouwrance Peter Wright
Mar 7, 2021·Proceedings of the National Academy of Sciences of the United States of America·Sirsha MitraLouwrance P Wright
Aug 26, 2021·Annual Review of Phytopathology·Pradeep KachrooMurray Grant
Oct 21, 2021·Molecular Plant-microbe Interactions : MPMI·Nikoleta RubilLenka Burketová

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Methods Mentioned

BETA
PCR
environmental stresses

Software Mentioned

SPSS

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