The platelet membrane as a catalytic surface in thrombin generation: availability of platelet factor 1 and platelet factor 3

Thrombophilia includes conditions with increased tendency for excessive blood clotting. Blood clotting occurs when the body has insufficient amounts of specialized proteins that make blood clot and stop bleeding. Here is the latest research on blood clotting disorders.

The platelet membrane as a catalytic surface in thrombin generation: availability of platelet factor 1 and platelet factor 3

Abstract

References

Interaction of coagulation factor Xa with human platelets.

Membrane and lipid involvement in blood coagulation

Current concepts of platelet structure

A computer program for analysis of clotting factor assays and other parallel-line bioassays

Phospholipid-binding properties of bovine factor V and factor Va

Patients with congenital factor V deficiency have decreased factor Xa binding sites on their platelets

Isolation of human platelets and platelet surface membranes

Recent advances in platelet lipid metabolism research

Formation of an intermediate in prostaglandin biosynthesis and its association with the platelet release reaction

Chemical characterization of fragments produced in the conversion of bovine prothrombin to thrombin by activated factor X

Adenine nucleotide metabolism of blood platelets. VI. Subcellular localization of nucleotide pools with different functions in the platelet release reaction

Platelets and their plasma cofactor activity in the activation of purified prothrombin

Differentiation of certain platelet factors related to blood coagulation

Platelet factor 1 related to prothrombin activation

Platelet extracts, fibrin formation and interaction of purified prothrombin and thromboplastin

Citations

Differentiation of factor V-like coagulant activity from catalytic phospholipid-like surface activity in membrane fractions derived from human platelets

Surface-governed molecular regulation of blood coagulation

Hematological change in venous blood of the lower leg during prolonged sitting in a low humidity and hypobaric environment

Expression of coagulant activity in human platelets: release of membranous vesicles providing platelet factor 1 and platelet factor 3

Analysis of platelet factor 3 in platelet concentrates stored for transfusion

Phase behavior of mixed phosphatidylglycerol/phosphatidylcholine multilamellar and unilamellar vesicles

Oral contraceptive steroid induced platelet coagulant hyperactivity: dissociation of in vivo and in vitro effects

Association of factor V activity with membranous vesicles released from human platelets: requirement for platelet stimulation

Comparison of the abilities of synthetic and platelet-derived membranes to enhance thrombin formation

Cutaneous tissue repair: basic biologic considerations. I

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