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The Pleiotropic Effects of Statins - From Coronary Artery Disease and Stroke to Atrial Fibrillation and Ventricular Tachyarrhythmia

Current Vascular Pharmacology

Aug 21, 2018

Adam Oesterle, James K Liao

Abstract

Statins, 3-hydroxy-methylglutaryl coenzyme A reductase inhibitors, have been used for decades for the prevention of coronary artery disease and stroke. They act primarily by lowering serum cholesterol through the inhibition of cholesterol synthesis in the liver, which results in the upr...read more

Mentioned in this Paper

EEF1A2
Study
Plaque, Atherosclerotic
Coronary Artery Disease
Cholesterol Biosynthetic Process
Coenzyme A
Oxidase
Subtilisins
Anti-Arrhythmia Agents
Antiarrhythmic [EPC]
Paper Details
References
  • References140
  • Citations3
12345...
  • References140
  • Citations3
1

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Pleiotropic Effects of Statins on the Cardiovascular System(opens in new tab)

Circulation ResearchJanuary 7, 2017
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The Pleiotropic Effects of Statins - From Coronary Artery Disease and Stroke to Atrial Fibrillation and Ventricular Tachyarrhythmia

Current Vascular Pharmacology

Aug 21, 2018

Adam Oesterle, James K Liao

PMID: 30124154

DOI: 10.2174/1570161116666180817155058

Abstract

Statins, 3-hydroxy-methylglutaryl coenzyme A reductase inhibitors, have been used for decades for the prevention of coronary artery disease and stroke. They act primarily by lowering serum cholesterol through the inhibition of cholesterol synthesis in the liver, which results in the upr...read more

Mentioned in this Paper

EEF1A2
Study
Plaque, Atherosclerotic
Coronary Artery Disease
Cholesterol Biosynthetic Process
Coenzyme A
Oxidase
Subtilisins
Anti-Arrhythmia Agents
Antiarrhythmic [EPC]

Feeds With Similar Papers

Atherosclerosis Disease Progression

Atherosclerosis is the buildup of plaque on artery walls, causing stenosis which can eventually lead to clinically apparent cardiovascular disease. Find the latest research on atherosclerosis disease progression here.

Platelet Activation

Platelets are a blood cell that can initiate clot formation in response to damage to blood vessels. Following platelet adhesion, platelets become activated before aggregating. Find the latest research on platelet activation here.

Related Papers

Circulation Research

Pleiotropic Effects of Statins on the Cardiovascular System(opens in new tab)

Circulation ResearchJanuary 7, 2017
Adam OesterleJames K Liao
Paper Details
References
  • References140
  • Citations3
12345...
  • References140
  • Citations3
1

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