The position effect in mice on day 14

Teratology
H von DomarusF Lange-Wühlisch

Abstract

Previous publications have produced conflicting results concerning the effect and nature of uterine horn position on embryonic weight and development in the uterus bicornis. For this investigation we used 503 embryos from 41 litters of NMRI - mice on gestational day 14. The relative position of each embryo was determined by measuring the distance from the center of each placenta to the cervix in relation to the total length of the uterine horn. After cessation of shrinkage due to fixation the umbilical cord and remaining membranes were removed under the dissecting microscope and the embryos were weighed to the nearest 0.1 mg. Analysis of potential embryonic positions along the uterine horns indicated that 10% at the extreme ovarian and cervical ends were almost devoid of implantations. A mixed nested analysis of variance was used as the appropriate model to test a position on weight effect. Not only was a position effect found but, in contrast to other studies, it is also quantitatively represented. Embryos were lighter both at the ovarian and cervical ends, the mean weight difference being in the range of less than 10% of the average embryo weight.

References

Apr 1, 1979·Teratology·N A Norman, N W Bruce
Nov 1, 1979·Journal of Reproduction and Fertility·N A Norman, N W Bruce
Mar 1, 1976·Journal of Reproduction and Fertility·L L Anderson, R O Parker
Jun 1, 1970·The American Journal of Anatomy·R P JenshM Barr
Aug 1, 1970·The American Journal of Anatomy·M BarrR L Brent
Aug 1, 1969·Journal of Reproduction and Fertility·J S Perry, J G Rowell
Dec 1, 1981·Teratology·H von Domarus, T Louton
Nov 1, 1981·Journal of Toxicology and Environmental Health·J L StuckhardtS B Harris
Feb 1, 1965·Journal of Reproduction and Fertility·A MCLAREN

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Citations

Jul 1, 1988·Teratology·T LoutonP Hartmann
Jun 18, 2005·Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas·I Chahoud, F J R Paumgartten

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