PMID: 9540270Apr 16, 1998Paper

The possible role of bacterial superantigens in the pathogenesis of autoimmune disorders

Immunology Today
J SchiffenbauerH M Johnson

Abstract

The ability of superantigens (SAgs) to activate the immune system suggests that they may play a role in the course of autoimmune disorders. Here, Joel Schiffenbauer and colleagues review evidence from animal models of autoimmunity, as well as human data that support this hypothesis, and propose a model for SAg involvement in autoimmune disorders.

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