The Post-Surgical Long-Term Behaviour of Lung Carcinoid Tumours

The Indian Journal of Surgery
Antonio TancrediGerardo Scaramuzzi

Abstract

Here, we report a retrospective evaluation of long-term behaviour of lung carcinoids after surgery. A total of 23 patients (17 with typical pulmonary carcinoids and 6 with atypical pulmonary carcinoids) were enrolled in our hospital from April 1994 to July 2009. All patients underwent intervention at the Unit of Surgery and then were followed at the Unit of Oncology. The standard protocol for patient monitoring consisted of follow-up at 3 months after surgery, 6 months after first control and annually for 5 years. The follow-up evaluations consisted in blood tests, imaging of chest and abdomen, bone scintigraphy, and brain computed tomography. In case of disease recurrence, patients underwent chemotherapy (etoposide, carboplatin) and radiotherapy. All patients were followed for a mean of follow-up period of 100 months, ranging between 20 and 203 months. In the group of typical carcinoid, the observed recurrence rate at 5 years was zero, at 10 years was 5.8 %, whereas the observed mortality rate at 5 and 10 years was zero. In the group of atypical carcinoid, both the recurrence rate and the mortality rate at 5 and 10 years were 16.6 %. A statistical significant difference (p = 0.002) in the recurrence rate between stage I and st...Continue Reading

References

Aug 1, 1993·Mayo Clinic Proceedings·D G DavilaP C Pairolero
Apr 16, 2004·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·Lori J WirthBruce E Johnson
May 21, 2004·Annals of Oncology : Official Journal of the European Society for Medical Oncology·K ObergB Wiedenmann
Dec 31, 2005·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Hisao AsamuraKanji Nagai
Jun 27, 2006·The Journal of Thoracic and Cardiovascular Surgery·Heyman LuckrazEric G Butchart
Jun 27, 2006·Annals of Oncology : Official Journal of the European Society for Medical Oncology·N FazioK Öberg
Jul 4, 2006·Journal of the National Comprehensive Cancer Network : JNCCN·Lin-Chi ChenLee M Krug
Mar 27, 2007·The Journal of Thoracic and Cardiovascular Surgery·Hes A P BrokxTom G Sutedja
Mar 8, 2013·Interactive Cardiovascular and Thoracic Surgery·Jonathan AfokeMustafa Zakkar

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