PMID: 490184Jun 1, 1979Paper

The postnatal development of large light and small dark neurons in mouse dorsal root ganglia: a statistical analysis of cell numbers and size

Journal of Neurocytology
S N Lawson

Abstract

A method is described for the analysis of cell types in mouse dorsal root ganglia using the distribution of cell cross-sectional areas measured at the level of the nucleolus in 1.5 micron Epon sections. Using a computer program it was possible to demonstrate the existence of two normally distributed sub-populations of neurons in all the 3rd lumbar segment ganglia (17 in number) measured at various ages from birth to 70 days. The two populations appeared to correspond with large light cells and small dark cells. The large light cell bodies increased in size until about 20 days postnatal, subsequently their size decreased whereas the mean size of the small dark cells reached a plateau by about day 10. The relationship of both nuclear volume and surface area to the surface area of the perikaryon differed between light and dark cells. The number of neurons in L3 remained virtually constant at about 6000 throughout the period examined. Since the proportion of neurons in each population was not shown to change with age there was no evidence that cells could change from one type into the other.

References

May 1, 1978·Journal of Neuropathology and Experimental Neurology·Y Kawamura, P J Dyck
Jun 1, 1979·Journal of Neurocytology·S N Lawson, T J Biscoe
Jun 24, 1977·Brain Research·S N LawsonT H Williams
Aug 1, 1977·Journal of Neurocytology·L W Duchen, F Scaravilli
Feb 1, 1975·Proceedings of the National Academy of Sciences of the United States of America·J M Boutry, A B Nivikoff
Jan 1, 1971·Histochemie. Histochemistry. Histochimie·R Sarrat
May 1, 1974·Journal of the Neurological Sciences·M OtaP J Dyck
Aug 1, 1973·Developmental Medicine and Child Neurology·J L Emery, R Singhal
Jan 1, 1970·Histochemie. Histochemistry. Histochimie·M Kalina, M Wolman
Feb 1, 1946·The Anatomical Record·M ABERCROMBIE

❮ Previous
Next ❯

Citations

Jan 1, 1985·Cell and Tissue Research·D C TaylorJ Szolcsányi
Feb 1, 1983·Journal of Neurocytology·A RambourgA Beaudet
Jun 1, 1979·Journal of Neurocytology·S N Lawson, T J Biscoe
May 20, 2005·Cell and Tissue Research·Raymond E PapkaMegan Storey-Workley
Apr 17, 2008·Journal of Molecular Histology·Katarina VukojevicMirna Saraga-Babic
Oct 2, 1992·Brain Research·J M CaffreyJ D Kocsis
Nov 1, 1994·Journal of Neuroscience Methods·H Z TangR Hammerschlag
Dec 1, 1990·Brain Research. Developmental Brain Research·J J Pacifico, S A Scott
Feb 19, 1993·Brain Research. Developmental Brain Research·V MayeuxJ Valmier
Aug 29, 1986·Neuroscience Letters·B Key, P P Giorgi

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.