The posttranscriptional regulator RsmA plays a role in the interaction between Pseudomonas aeruginosa and human airway epithelial cells by positively regulating the type III secretion system.

Infection and Immunity
Heidi MulcahyFergal O'Gara

Abstract

Posttranscriptional regulation of certain virulence-related genes in Pseudomonas aeruginosa is brought about by RsmA, a small RNA-binding protein. During interaction with airway epithelial cells, RsmA promoted actin depolymerization, cytotoxicity, and anti-internalization of P. aeruginosa by positively regulating the virulence-associated type III secretion system.

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Citations

Nov 13, 2012·Nucleic Acids Research·Deepak BalasubramanianKalai Mathee
Jul 18, 2012·Antimicrobial Agents and Chemotherapy·Li MaLixin Zhang
May 4, 2011·Antimicrobial Agents and Chemotherapy·Isabel Pérez-Martínez, Dieter Haas
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Feb 22, 2018·Journal of Bacteriology·Kayley H JanssenTimothy L Yahr
Apr 3, 2015·Microbiology and Molecular Biology Reviews : MMBR·Christopher A VakulskasTony Romeo
Nov 16, 2018·Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia·Patrik Mlynarcik, Milan Kolar
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Apr 24, 2019·Journal of Bacteriology·Emily A Williams McMackinTimothy L Yahr
Dec 8, 2020·Frontiers in Microbiology·Yasuhiko IrieVictoria Shingler

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