The predicted subcellular localisation of the sugarcane proteome

Functional Plant Biology : FPB
Renato Vicentini, Marcelo Menossi

Abstract

Plant cells are highly organised, and many biological processes are associated with specialised subcellular structures. Subcellular localisation is a key feature of proteins, since it is related to biological function. The subcellular localisation of such proteins can be predicted, providing information that is particularly relevant to those proteins with unknown or putative function. We performed the first in silico genome-wide subcellular localisation analysis for the sugarcane transcriptome (with 11 882 predicted proteins) and found that most of the proteins were localised in four compartments: nucleus (44%), cytosol (19%), mitochondria (12%) and secretory destinations (11%). We also showed that ~19% of the proteins were localised in multiple compartments. Other results allowed identification of a potential set of sugarcane proteins that could show dual targeting by the use of N-truncated forms that started from the nearest downstream in-frame AUG codons. This study was a first step in increasing knowledge about the subcellular localisation of the sugarcane proteome.

References

Apr 1, 1989·European Journal of Biochemistry·G von HeijneR G Herrmann
Oct 1, 1995·Molecular Membrane Biology·S L Rusch, D A Kendall
Nov 1, 1996·European Journal of Biochemistry·M G Claros, P Vincens
Apr 25, 1997·Journal of Molecular Biology·C Burge, S Karlin
Apr 4, 1998·Journal of Theoretical Biology·T D Schneider
Mar 26, 1998·Journal of Molecular Biology·M A AndradeB Rost
Jul 13, 2000·Journal of Molecular Biology·O EmanuelssonG von Heijne
Mar 22, 2001·EMBO Reports·M CokolB Rost
Feb 16, 2002·Bioinformatics·Hideo BannaiSatoru Miyano
May 2, 2003·Bioinformatics·Cristian I Castillo-Davis, Daniel L Hartl
Dec 3, 2003·TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·H-M MaA Paterson
Dec 19, 2003·Nucleic Acids Research·Tao GuoZhirong Sun
Dec 19, 2003·Nucleic Acids Research·Evelyn CamonRolf Apweiler
Jun 25, 2004·Nucleic Acids Research·Karsten HillerDieter Jahn
Feb 11, 2005·Current Opinion in Chemical Biology·Nancy A O'RourkeGrischa Chandy
May 27, 2005·Applied Biochemistry and Biotechnology·Adalberto Pessoa-JrThereza Christina Vessoni Penna
Sep 29, 2005·Bioinformatics·Sean D Hooper, Peer Bork
Sep 23, 2006·Journal of Experimental Botany·Patrick MoreauBéatrice Satiat-Jeunemaitre
Sep 30, 2006·Current Opinion in Plant Biology·A Harvey MillarIan Small
Oct 13, 2006·Journal of Experimental Botany·John E Lunn
Oct 31, 2006·Nucleic Acids Research·Joshua L HeazlewoodA Harvey Millar
Nov 14, 2006·Nucleic Acids Research·Christian von MeringPeer Bork
Aug 3, 2007·Nucleic Acids Research·Jie LiuTongbin Li
Aug 7, 2007·Plant Physiology·Jane Geisler-LeeMatt Geisler
Oct 5, 2007·Current Opinion in Plant Biology·Kathryn S Lilley, Paul Dupree

❮ Previous
Next ❯

Citations

Oct 27, 2010·Plant Physiology·Cristiana Gomes de Oliveira Dal'MolinLars Keld Nielsen

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.