The Predictive Role of Intraoperative Visual Evoked Potentials in Visual Improvement After Endoscopic Pituitary Tumor Resection in Large and Complex Tumors: Description and Validation of a Method

World Neurosurgery
Rui FengRaj Shrivastava

Abstract

With the advent of extensive endoscopic approaches for pituitary tumors, there has also been an increase in surgery for larger and more complex tumors. Intraoperative manipulation during endoscopic resection of sellar tumors poses potential risk in postoperative visual function in this tumor population. This study proposes a method of accurate intraoperative monitoring of visual evoked potentials (VEPs) and its role in predicting visual function outcomes. Intraoperative VEPs were monitored for 42 resections from a single surgical team, with average tumor size of 2.84 cm. Changes in VEP amplitude and latency in excess of 50% were considered significant. Preoperative and postoperative visual information was obtained from ophthalmology and hospital records, along with patient demographics, comorbidities, and tumor characteristics. Patients were stratified as experiencing deteriorations in VEPs that did not restore to baseline (n = 4), deteriorations in VEPs that did restore to baseline (n = 6), no change in VEPs (n = 31), and improvement in VEPs (n = 1). Correlation between VEP changes and postoperative visual fields was measured through univariate ordered logistic regression. Improved intraoperative VEP measurements were associat...Continue Reading

References

Jan 1, 1990·International Anesthesiology Clinics·C Cedzich, J Schramm
Mar 1, 1988·Electroencephalography and Clinical Neurophysiology·C CedzichR Fahlbusch
Jun 1, 1988·Surgical Neurology·P M BlackG Candia
May 1, 1995·Australian and New Zealand Journal of Ophthalmology·A PoonJ O'Day
Jun 1, 1997·The Journal of Laryngology and Otology·N S Jones
Dec 22, 2000·American Journal of Ophthalmology·J B KerrisonN J Newman
Dec 25, 2002·Journal of Neurosurgical Anesthesiology·Helmut WiedemayerDietmar Stolke
Jan 16, 2007·Arquivos de neuro-psiquiatria·Jackson A GondimMichele Schops
Feb 4, 2010·Acta neurochirurgica·Kunihiko KodamaKazuhiro Hongo
Feb 26, 2011·Korean Journal of Ophthalmology : KJO·Jung Pil LeeYun Suk Chung
Oct 27, 2015·AJR. American Journal of Roentgenology·In Ho LeeMichael V Boland
Feb 28, 2017·Neurologia Medico-chirurgica·Hiroshi Nishioka

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