The PREgnancy and FERtility (PREFER) study: an Italian multicenter prospective cohort study on fertility preservation and pregnancy issues in young breast cancer patients

BMC Cancer
Matteo LambertiniLucia Del Mastro

Abstract

Fertility and pregnancy issues are of key importance for young breast cancer patients. Despite several advances in the field, there are still multiple unmet needs and barriers in discussing and dealing with these concerns. To address the significant challenges related to fertility and pregnancy issues, the PREgnancy and FERtility (PREFER) study was developed as a national comprehensive program aiming to optimize care and improve knowledge around these topics. The PREFER study is a prospective cohort study conducted across several Italian institution affiliated with the Gruppo Italiano Mammella (GIM) group evaluating patterns of care and clinical outcomes of young breast cancer patients dealing with fertility and pregnancy issues. It is composed of two distinctive studies: PREFER-FERTILITY and PREFER-PREGNANCY. The PREFER-FERTILITY study is enrolling premenopausal patients aged 18-45 years, diagnosed with non-metastatic breast cancer, who are candidates to (neo)adjuvant chemotherapy and not previously exposed to anticancer therapies. The primary objective is to obtain and centralize data about patients' preferences and choices towards the available fertility preserving procedures. The success and safety of these strategies and t...Continue Reading

Associated Clinical Trials

Sep 9, 2016·Lucia Del Mastro,MD

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Citations

Feb 3, 2020·Journal of Assisted Reproduction and Genetics·Mary E Hampe, Alice S Rhoton-Vlasak
Feb 6, 2020·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Cynthia Villarreal-GarzaAlejandro Mohar
Dec 15, 2020·Trends in Molecular Medicine·Marie-Madeleine DolmansLuciana Cacciottola
May 29, 2021·Journal of the National Cancer Institute·Wanyuan CuiKelly-Anne Phillips

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Methods Mentioned

BETA
biopsy
X-ray

Software Mentioned

PREFER

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