The Presence and Degree of Bone Marrow Edema Influence Midterm Clinical Outcomes After Microfracture for Osteochondral Lesions of the Talus

The American Journal of Sports Medicine
Yoshiharu ShimozonoJohn G Kennedy

Abstract

Subchondral bone marrow edema (BME) has been associated with articular cartilage loss, with the potential to be a negative prognostic indicator for clinical outcomes after microfracture. However, no single study has investigated the association between BME and clinical outcomes after microfracture for osteochondral lesions of the talus (OLTs) at midterm follow-up. To clarify the association between postoperative subchondral BME and clinical outcomes in patients treated with microfracture for OLTs at both short-term and midterm follow-up using a grading system that classified the extent of BME of the talus. Cohort study; Level of evidence, 3. Patients who underwent microfracture between 2008 and 2013 were assessed at 2- and 4-year postoperative follow-up. BME was evaluated using magnetic resonance imaging, and the presence of subchondral BME was determined with fat-suppressed T2-weighted sequences. Clinical outcomes were evaluated using the Foot and Ankle Outcome Score (FAOS). P < .05 was considered to be statistically significant. Forty-three (83%) of 52 eligible patients were included. No significant differences were found in the FAOS between the BME and no BME groups at 2-year follow-up (83.1 ± 6.5 vs 88.6 ± 8.0, respectively...Continue Reading

References

Jan 1, 1984·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·T D Brown, M S Vrahas
May 17, 2000·The Journal of Bone and Joint Surgery. British Volume·B HintermannA Gächter
Oct 18, 2001·Clinical Orthopaedics and Related Research·J R SteadmanJ J Rodrigo
Oct 20, 2001·Foot & Ankle International·E M RoosJ Karlsson
Dec 18, 2001·Seminars in Musculoskeletal Radiology·L AlparslanT Minas
Sep 11, 2003·Annals of Internal Medicine·David T FelsonDaniel Gale
Oct 1, 2003·The Journal of Bone and Joint Surgery. British Volume·I J P HendersonW H Hettwer
Apr 20, 2005·European Journal of Radiology·Joshua Polster, Michael Recht
May 23, 2008·European Journal of Radiology·Stefan Franz NemecSiegfried Trattnig
Aug 30, 2008·The American Journal of Sports Medicine·Richard D FerkelRyan M Dopirak
Aug 6, 2009·The American Journal of Sports Medicine·Woo Jin ChoiJin Woo Lee
Feb 2, 2010·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·Henning MadryMagdalena Mueller-Gerbl
Feb 5, 2010·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·Christoph BecherHajo Thermann
Aug 20, 2010·The Journal of Bone and Joint Surgery. American Volume·Lisa A FortierAlan J Nixon
Oct 11, 2011·The American Journal of Sports Medicine·Woo Jin ChoiJin Woo Lee
Dec 4, 2012·Foot & Ankle International·Lan ChenScott J Ellis
Mar 21, 2013·Foot & Ankle International·Sriniwasan B ManiScott J Ellis
May 15, 2013·Arthroscopy : the Journal of Arthroscopic & Related Surgery : Official Publication of the Arthroscopy Association of North America and the International Arthroscopy Association·Niall A SmythJohn G Kennedy
Dec 18, 2013·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·Giuseppe FilardoMaurilio Marcacci
Aug 30, 2014·The American Journal of Sports Medicine·Mona EldracherHenning Madry
Feb 13, 2015·Journal of the American Podiatric Medical Association·Nicolò MartinelliFrancesco Malerba
Sep 24, 2015·Arthroscopy : the Journal of Arthroscopic & Related Surgery : Official Publication of the Arthroscopy Association of North America and the International Arthroscopy Association·Charles P HannonJohn G Kennedy
Nov 8, 2015·The American Journal of Sports Medicine·Patrick OrthHenning Madry
Feb 3, 2016·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·Jennifer M CassanoLisa A Fortier
May 29, 2016·Arthroscopy : the Journal of Arthroscopic & Related Surgery : Official Publication of the Arthroscopy Association of North America and the International Arthroscopy Association·Arianna L GianakosJohn G Kennedy
Jul 29, 2017·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·Mikel L ReilinghGino M M J Kerkhoffs
Nov 17, 2017·The American Journal of Sports Medicine·Yoshiharu ShimozonoJohn G Kennedy

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Citations

Jun 9, 2020·The American Journal of Sports Medicine·Michael J CarlsonRichard D Ferkel
Mar 5, 2021·The American Journal of Sports Medicine·Jae Han ParkJin Woo Lee
Mar 14, 2021·Orthopaedics & Traumatology, Surgery & Research : OTSR·Ronny LopesThomas Amouyel

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