PMID: 3753943Feb 1, 1986Paper

The presence of Müllerian remnants in the complete androgen insensitivity syndrome: a steroid hormone-mediated defect?

Fertility and Sterility
A Ulloa-AguirreG Pérez-Palacios

Abstract

A new patient with CAIS who presented Müllerian remnants has been described. Based on recently reported data in experimental animals and considering that human embryos carrying the X-linked CAIS mutation do not express any androgenic effect, we propose that the unopposed estrogenic action in the CAIS-developing embryo might interfere with the mechanism of action of the AMH inhibiting the regression of the female ducts.

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