The prevalence and risk factors for hepatitis B surface ag positivity in pregnant women in eastern region of ghana.

Gut and Liver
Younmo ChoMoran Ki

Abstract

The aim of this study was to evaluate the prevalence and risk factors for hepatitis B surface antigen (HBsAg) positivity in pregnant Ghanaian women. We surveyed 1,500 pregnant women in Eastern region of Ghana. Direct interviews were performed by trained nurses using standardized questionnaires. Pregnant women were screened for human immunodeficiency virus (HIV) and hepatitis B infections, hemoglobin levels and sickle cell anemia as part of the antenatal check-up. The overall HBsAg positive rate was 10.6%, which varied among districts (13.8% for Kwahu West, 12.4% for Upper Manya, and 2.2% for Yilo Krobo). HBsAg positivity was significantly higher in women with depression (odds ratio [OR], 3.74; 95% confidence interval [CI], 2.13 to 6.57) and HIV (OR, 2.03; 95% CI, 1.06 to 3.89). Age, education, and gravidity were not related to HBsAg positivity. Anti-hepatitis B immunoglobulin for newborns of HBsAg-positive mothers is not provided at birth in public health facilities in Ghana. However, hepatitis B vaccination is provided as part of a routine vaccination schedule starting at 6 weeks of age. To prevent mother-to-child transmission of hepatitis B, screening tests for HBsAg in pregnant women and hepatitis B vaccination of newborns i...Continue Reading

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Citations

Mar 6, 2013·Expert Review of Anti-infective Therapy·Sara A HealyAnn J Melvin
Feb 7, 2016·Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology·Rania A TohmeSaleem Kamili
Mar 19, 2016·BMC Infectious Diseases·Richard Ofori-Asenso, Akosua Adom Agyeman
May 18, 2016·AIDS Research and Therapy·Akosua Adom Agyeman, Richard Ofori-Asenso
Oct 10, 2018·The American Journal of Tropical Medicine and Hygiene·Charles Ampong AdjeiWilliam Menkah
Jun 30, 2019·BMJ Open·Charles Ampong AdjeiRobert A C Ruiter
Jul 19, 2016·Tropical Medicine & International Health : TM & IH·Svetlana PopovaJürgen Rehm
May 16, 2020·International Journal of Hepatology·Precious Kwablah KwadzokpuiPhilip Apraku Tawiah
Jun 7, 2017·BMC Pregnancy and Childbirth·Fabian VölkerUwe Groß

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