DOI: 10.1101/19008961Oct 18, 2019Paper

The prevalence and risk factors for phantom limb pain in people with amputations: a systematic review and meta-analysis.

MedRxiv : the Preprint Server for Health Sciences
Katleho LimakatsoRomy Parker


Background and objective Phantom limb pain (PLP) is a common complication in people with limb amputations. There are conflicting reports in the literature regarding the prevalence of PLP in people with limb amputations. Therefore, this review aimed to determine the estimated pooled prevalence of PLP, and risk factors associated with this complication. Methods Articles published between 1980 and July 2019 were identified through a systematic search of the following electronic databases: MEDLINE/PubMed, PsycINFO, PsycArticles, Cumulative Index to Nursing and Allied Health Literature, Africa-Wide Information, Health Source: Nursing/Academic Edition, SCOPUS, Web of Science and Academic Search Premier. Grey literature was searched on databases for preprints. Two reviewers independently performed the screening of articles, data extraction and risk of bias assessment. The meta-analyses were conducted using the random-effects model. A statistically significant level for the analyses was set at p>0.05. Results The pooling of all studies demonstrated a prevalence estimate of 63% [95% CI: 58.23-67.05] with high heterogeneity [I2=95.70% (95% CI: 95.10-96.20)]. The prevalence of PLP was significantly lower in developing countries compared t...Continue Reading

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