The Prevalence of Asymptomatic and Symptomatic Spinal Cord Compression on Magnetic Resonance Imaging: A Systematic Review and Meta-analysis.

Global Spine Journal
Sam S SmithMark R N Kotter

Abstract

Systematic review and meta-analysis. Cervical spinal cord compression (SCC) due to degenerative changes of the spine is a frequent finding on magnetic resonance imaging (MRI). While most people remain asymptomatic, a proportion develop symptoms of degenerative cervical myelopathy (DCM). DCM is an often-progressive neurological disease that can cause quadriplegia. The epidemiology of SCC and DCM is poorly understood. We sought to estimate the prevalence of degenerative cervical SCC and DCM from cross-sectional cohorts undergoing MRI. We conducted a systematic review and meta-analysis of MRI reports on human subjects older than 16 years with degenerative SCC. A predetermined search strategy was used to identify relevant literature on MEDLINE. Title and abstract screenings were followed by full text screening. Data was extracted and analyzed by fixed or random-effects models. The present search returned 1506 publications. Following our exclusion criteria, 19 studies were included. Subgroup analysis of 3786 individuals estimated the prevalence of asymptomatic SCC in a healthy population as 24.2% with a significantly higher prevalence of SCC in older populations compared with younger populations and American/European populations com...Continue Reading

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Citations

Feb 25, 2021·Acta neurochirurgica·Ben GrodzinskiBenjamin Davies
Apr 4, 2021·Journal of Clinical Medicine·Zdenek KadankaJosef Bednarik
Jul 20, 2021·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Aref-Ali GharooniMark Kotter
Jul 22, 2021·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·Jan ValošekAlena Svatkova
Oct 11, 2021·Spinal Cord·Carl M ZipserUNKNOWN Members of the Diagnostic Criteria Working Group

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