The Prevalence of Concomitant Deep Vein Thrombosis, Symptomatic or Asymptomatic, Proximal or Distal, in Patients With Symptomatic Pulmonary Embolism

Clinical and Applied Thrombosis/hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
J HirmerovaZdenek Chudacek

Abstract

Patients with pulmonary embolism (PE) may have symptomatic or asymptomatic concomitant deep vein thrombosis (DVT). The reported prevalence of PE-associated DVT is variable, and thus, the utility of routine testing is controversial. The aim of our study was to analyze the prevalence of DVT and the factors associated with proximal DVT/whole-leg DVT in patients with symptomatic PE. In 428 consecutive patients (mean age: 59 ± 16.4 years; 52.3% men), we performed clinical examination and complete bilateral compression ultrasound and ascertained medical history and risk factors for DVT/PE. χ2 and t tests were used. Deep vein thrombosis was found in 70.6%; proximal DVT in 49.5%. Sensitivity/specificity of DVT symptoms was 42.7%/93.7% for whole-leg DVT and 47.6%/83.3% for proximal DVT. Male gender significantly prevailed among those with whole-leg DVT and with proximal DVT (58.9% and 61.8%). Active malignancy was significantly more frequent in the patients with proximal DVT than without proximal DVT (10.4% vs 3.7%). In conclusion, the prevalence of PE-associated DVT is quite high but clinical diagnosis is unreliable. In our group, male gender and active malignancy were significantly associated with the presence of concomitant proximal ...Continue Reading

References

May 13, 1999·The British Journal of Radiology·A B van RossumP M Pattynama
May 7, 2002·Clinical and Applied Thrombosis/hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis·Thomas SchwarzSebastian M Schellong
Sep 16, 2005·Chest·Philippe GirardUNKNOWN Evaulation du Scanner Spiralé dans l'Embolie Pulmonaire Study Group
Nov 2, 2007·Journal of Thrombosis and Haemostasis : JTH·F A KlokM V Huisman
Jan 25, 2008·Thrombosis and Haemostasis·Nadine S GibsonUNKNOWN Christopher study investigators
Oct 17, 2008·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·T YamakiT Kono
Oct 29, 2008·Archives of Internal Medicine·Frederikus A KlokMenno V Huisman
Nov 20, 2008·Annals of Internal Medicine·Susan R KahnJeffrey S Ginsberg
Jan 26, 2010·Journal of Thrombosis and Haemostasis : JTH·H Robert-EbadiM Righini
Jan 30, 2010·American Journal of Respiratory and Critical Care Medicine·David JiménezUNKNOWN RIETE Investigators
Mar 2, 2010·European Journal of Epidemiology·Cornelia SchneiderChristoph R Meier
Nov 16, 2011·Journal of Thrombosis and Haemostasis : JTH·Gualtiero Palareti, S Schellong
Apr 13, 2012·Lancet·Samuel Z Goldhaber, Henri Bounameaux
Jul 4, 2012·Annals of Vascular Surgery·Tim SchwartzTheresa Jacob
Sep 11, 2012·Best Practice & Research. Clinical Haematology·Hervé DecoususAlain Leizorovicz
May 23, 2014·Thorax·Christopher KabrhelYuchiao Chang
Sep 1, 2014·European Heart Journal·Stavros V KonstantinidesUNKNOWN Task Force for the Diagnosis and Management of Acute Pulmonary Embolism of the European Society of Cardiology (ESC)

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Citations

Jun 27, 2019·Journal of Clinical Medicine·Elena-Mihaela CordeanuDominique Stephan
Mar 22, 2021·The American Journal of Emergency Medicine·Mehmet EkiciŞule İleri

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