The prevalence of cutaneous hypersensitivity and its relationship to Pseudomonas colonization and outcome in cystic fibrosis

Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology
A H Hamilton, F Carswell

Abstract

Forty-seven patients with cystic fibrosis (CF) studied in 1977 have been followed up and reviewed, with respect to the development of immediate cutaneous hypersensitivity to Aspergillus fumigatus and other allergens, and the date of Pseudomonas aeruginosa colonization. The prevalence of cutaneous hypersensitivity to inhaled allergens in CF increases with longer allergen exposure, to the extent that the CF patients develop a prevalence of atopy greater than normal controls. Allergen-sensitive patients were found to develop Pseudomonas colonization later, but to have a shorter survival subsequently; there was no relationship between skin tests and overall survival.

References

Nov 1, 1978·Archives of Disease in Childhood·M SilvermanF Carswell
Jul 1, 1976·Archives of Disease in Childhood·J O WarnerJ F Soothill
Jul 1, 1986·The Journal of Infection·P A Friend
May 14, 1988·British Medical Journal·D Machin, M J Gardner
Sep 1, 1986·Annals of Internal Medicine·R Simon
Jul 1, 1985·American Journal of Diseases of Children·R W WilmottD J Matthew
Sep 1, 1972·Clinical Allergy·S LeskowitzH J Schwartz
Jan 1, 1981·British Journal of Diseases of the Chest·C W ClarkeC Hannant
Aug 1, 1982·Archives of Disease in Childhood·R W Pitcher-WilmottD J Matthew

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Citations

Nov 26, 2003·Journal of the American Academy of Dermatology·Jared Samuel FriedmanJo-David Fine
Nov 1, 1990·Archives of Disease in Childhood·F Carswell, A Hamilton
Nov 13, 2012·Pediatric Pulmonology·Joseph M CollacoPeter J Mogayzel

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Aspergillosis (ASM)

Aspergillosis is the name given to a wide variety of diseases caused by infection by fungi of the genus Aspergillus. Aspergillosis occurs in chronic or acute forms which are clinically very distinct. Most cases of acute aspergillosis occur in patients with severely compromised immune systems. Chronic colonization or infection can cause complications in people with underlying respiratory illnesses. Discover the latest research on aspergillosis here.

Aspergillosis

Aspergillosis is the name given to a wide variety of diseases caused by infection by fungi of the genus Aspergillus. Aspergillosis occurs in chronic or acute forms which are clinically very distinct. Most cases of acute aspergillosis occur in patients with severely compromised immune systems. Chronic colonization or infection can cause complications in people with underlying respiratory illnesses. Discover the latest research on aspergillosis here.

Atopic Dermatitis

Atopic dermatitis is a chronic inflammatory genetically determined disease of the skin marked by increased ability to form reagin (IgE), with increased susceptibility to allergic rhinitis and asthma, and hereditary disposition to a lowered threshold for pruritus. Discover the latest research on atopic dermatitis here.

Allergy and Asthma

Allergy and asthma are inflammatory disorders that are triggered by the activation of an allergen-specific regulatory t cell. These t cells become activated when allergens are recognized by allergen-presenting cells. Here is the latest research on allergy and asthma.

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