PMID: 6965646Feb 1, 1980Paper

The prevalence of duodenal lesions in patients with rheumatic diseases on chronic aspirin therapy

Gastrointestinal Endoscopy
O O LockardS Holt

Abstract

Peroral endoscopy was performed in 56 patients with rheumatic disease who had been taking 8 or more aspirin tablets daily for more than 3 months yet who had no major gastrointestinal symptoms or history of peptic ulcer disease. Duodenal mucosal lesions were observed in 16 patients; 15 (27%) had erythema, 7 (13%) had erosions, and 2 (4%) had ulcers. The prevalence of duodenal lesions was the same in patients taking regular, buffered, or enteric-coated aspirin preparations. Patients with duodenal lesions were more likely to have associated gastric lesions.

References

May 1, 1974·The American Journal of Digestive Diseases·D C SunD W Englund

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Citations

Aug 1, 1987·Digestive Diseases and Sciences·M B KimmeyR C Chapman
Mar 1, 1989·Digestive Diseases and Sciences·M G RobinsonC W Warner
Jun 1, 1988·Digestive Diseases and Sciences·G L KauffmanJ Mangus
Jan 1, 1994·Digestive Diseases and Sciences·J M ScheimanG H Elta
Aug 26, 1998·The American Journal of Medicine·B Cryer, M B Kimmey
Jul 2, 1999·The American Journal of Medicine·J B Raskin
Aug 1, 1989·Baillière's Clinical Rheumatology·E L Semble, W C Wu
Aug 1, 1989·Baillière's Clinical Rheumatology·K J Ivey, P J Rooney
Jul 31, 1996·The American Journal of Medicine·D J Bjorkman
Sep 22, 2001·Best Practice & Research. Clinical Gastroenterology·D M McCarthy
Jan 1, 1987·Scandinavian Journal of Rheumatology. Supplement·M CucalaA L Blum
May 15, 1991·Postgraduate Medicine·F Silverstein

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