The prevalence of hematologic and metabolic abnormalities during chronic kidney disease stages in different ethnic groups

Kidney International
S J BarbourA Levin

Abstract

We conducted an observational cross-sectional study to determine if the prevalence of hematologic and metabolic abnormalities in chronic kidney disease (CKD) varied in different ethnic groups. We used a CKD provincial database where a complete data set at the time of registration was available as well as an estimated glomerular filtration rate (eGFR), which showed using the abbreviated MDRD formula that the patients had CKD of stages 3-5. We included patients with self-reported race of Caucasian, Oriental Asian, or South Asian. Primary outcomes were the prevalence of at least one of the following: anemia, hypocalcemia, hyperphosphatemia, hyperparathyroidism, hypoalbuminemia, and three or more laboratory abnormalities. All definitions were consistent with K/DOQI guidelines. When compared with Caucasians, Oriental Asians and South Asians had a higher prevalence of many of the metabolic abnormalities during most stages of CKD and were more likely to have any abnormality at all levels of eGFR. The prevalence of three or more laboratory abnormalities was higher in Oriental Asians at all stages and in South Asians at some levels of eGFR. These results were unchanged or exaggerated when controlled for age, gender, diabetes, and a prim...Continue Reading

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Citations

Aug 30, 2011·Journal of Feline Medicine and Surgery·Serge ChalhoubAdam Eatroff
Jun 5, 2013·Cardiology in the Young·Chaya Pitman-HuntChristopher W Mastropietro
Jul 9, 2008·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Anneleen PletinckRaymond Vanholder
Dec 25, 2009·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Ja-Liang LinYen-Lin Huang
Apr 7, 2010·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Sean J BarbourAdeera Levin
Oct 23, 2016·Research in Social & Administrative Pharmacy : RSAP·Zachariah NazarDavid Brown
Mar 11, 2016·The New England Journal of Medicine·Jürgen FloegeFrank Eitner
Sep 8, 2015·The British Journal of Social Psychology·Sabine CaillaudSilvia Krauth-Gruber
Feb 2, 2010·Renal Failure·Mitra Mahdavi-MazdehAzita Mahdavi
Sep 20, 2011·European Journal of Oncology Nursing : the Official Journal of European Oncology Nursing Society·Clare L DavidD W Owen Tilsley
Jul 17, 2019·Canadian Journal of Kidney Health and Disease·Aiza WaheedSean Barbour

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