The Prevalence of Metabolically Healthy and Unhealthy Obesity according to Different Criteria

Obesity Facts
Chunxiao LiuXianghua Fang

Abstract

Obesity-related disease risks may vary depending on whether the subject has metabolically healthy obesity (MHO) or metabolically unhealthy obesity (MUO). At least 5 definitions/criteria of obesity and metabolic disorders have been documented in the literature, yielding uncertainties in a reliable international comparison of obesity phenotype prevalence. This report aims to compare differences in MHO and MUO prevalence according to the 5 most frequently used definitions. A random sample of 4,757 adults aged 35 years and older (male 51.1%) was enrolled. Obesity was defined either according to body mass index or waist circumference, and the definitions of metabolic abnormalities were derived from 5 different criteria. In MHO, the highest prevalence was obtained when using the homeostasis model assessment (HOMA) criteria (13.6%), followed by the Chinese Diabetes Society (11.4%), Adult Treatment Panel III (10.3%), Wildman (5.2%), and Karelis (4.2%) criteria; however, the MUO prevalence had an opposite trend to MHO prevalence. The magnitude of differences in the age-specific prevalence of MHO and MUO varied greatly and ranked in different orders. The proportion of insulin resistance for MHO and MUO individuals differed significantly ...Continue Reading

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Citations

Mar 5, 2020·Endocrine Reviews·Matthias Blüher
May 23, 2020·Lipids in Health and Disease·Karianne SvendsenVibeke H Telle-Hansen
Sep 6, 2020·The American Journal of Clinical Nutrition·Claudia Martinez-TapiaFlorence Canouï-Poitrine
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Apr 4, 2021·International Journal of Environmental Research and Public Health·Wei-Lun WenSzu-Chia Chen
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Aug 14, 2021·Diabetes, Metabolic Syndrome and Obesity : Targets and Therapy·Xiaoyue ZhuBei Wang
Jul 7, 2020·Current Diabetes Reviews·Hend Al-JaberMohamed A Elrayess

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