The prevalence of pediatric metabolic syndrome-a critical look on the discrepancies between definitions and its clinical importance.

International Journal of Obesity : Journal of the International Association for the Study of Obesity
Carolin ReisingerNandu Goswami

Abstract

The Metabolic Syndrome (MetS) describes the clustering of cardio-metabolic risk factors-including abdominal obesity, insulin resistance, elevated blood pressure, high levels of triglycerides, and low levels of high-density lipoproteins-that increase the risk for developing cardiovascular diseases and type 2 diabetes mellitus. However, a generally accepted definition of MetS in pediatric patients is still lacking. The aim was to summarize current prevalence data of childhood MetS as well as to discuss the continuing disagreement between different pediatric definitions and the clinical importance of such diagnosis. A systematic literature search on the prevalence of pediatric MetS was conducted. Articles that were published during the past 5 years (2014-2019), using at least one of four predetermined classifications (International Diabetes Federation, Cook et al., Ford et al., and de Ferranti et al.), were included. The search resulted in 1167 articles, of which 31 publications met all inclusion criteria. The prevalence of MetS ranged between 0.3 and 26.4%, whereby the rising number of children and adolescents with MetS partly depended on the definition used. The IDF definition generally provided the lowest prevalences (0.3-9.5%)...Continue Reading

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Citations

Jun 3, 2021·Children·Valeria CalcaterraFatima Cody Stanford
Jun 27, 2021·Nutrition, Metabolism, and Cardiovascular Diseases : NMCD·Eline VermeirenKim Van Hoorenbeeck
Apr 15, 2021·Canadian Journal of Physiology and Pharmacology·Dávid MiláčekKatarína Šebeková
Oct 2, 2021·Journal of Pediatric Endocrinology & Metabolism : JPEM·Jagdish Prasad GoyalPraveen Sharma
Jun 26, 2021·The European Journal of Neuroscience·Jacqueline S WomersleySîan M J Hemmings

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